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blood vessel Archives

Vascular dysfunction during sepsis

Oct. 25, 2022—Regulation of the enzyme Sirtuin 1 in blood vessel endothelial cells may drive altered metabolism and vascular dysfunction during sepsis, Vanderbilt researchers have discovered.

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There’s no slowing arterial stiffening

Mar. 29, 2022—Over 10 years, multiple healthy behaviors did not slow the progression of arterial stiffness, a risk factor for coronary artery disease, hypertension, stroke, atrial fibrillation and heart failure.

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New strategy to treat brain bleeding

May. 4, 2021—Vasorelaxing peptides could offer a promising therapeutic strategy for reducing the neurological deficits caused by subarachnoid hemorrhage-induced cerebral blood vessel constriction.

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Brain blood vessel response to hypoxia

Oct. 15, 2020—The brain’s response to low oxygen — growth and remodeling of blood vessels — involves certain cell types and molecular pathways, Vanderbilt researchers have discovered.

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A “torque” for tumor blood vessels

Aug. 20, 2020—Vanderbilt scientists have discovered a new target for normalizing tumor blood vessels to improve cancer immunotherapies.

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Imaging probe for retinal disease

Oct. 12, 2016—An imaging probe developed at Vanderbilt detects retinal inflammation early and may allow therapeutic intervention to prevent blindness.

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Vitamin C protects blood vessel lining

Sep. 4, 2015—Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases.

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Aggressive bone cancers build more blood vessels

Sep. 3, 2014—A subpopulation of bone cancer cells may be responsible for driving clinically aggressive behavior, suggesting new treatment options.

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New direction for treating lung cancer

Feb. 7, 2014—Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer.

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Targeting tumor “supply lines”

Dec. 18, 2013—A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies.

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Tumor factor spurs blood vessel growth

Aug. 26, 2013—A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

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A role for blood vessels in delirium?

Apr. 15, 2013—Dysfunction of the endothelial cells that line blood vessels may contribute to delirium and coma in critically ill patients – and could be a target for therapy.

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