bone Archives
Diagnostic biomarker for bone disorder
Sep. 27, 2022—A urine chemical performs better as a diagnostic biomarker for the soft bone disease hypophosphatasia than other laboratory measures, Vanderbilt researchers have demonstrated.
Bone matrix changes during aging
Jan. 10, 2020—Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.
Keeping bone in its place
Apr. 11, 2019—Jonathan Schoenecker and colleagues have discovered a new mechanism for the formation of bone in soft tissues — a complication of severe injuries that causes pain and limits mobility.
Stress may switch on bone “mets”
Aug. 9, 2017—New findings could explain the link between chronic stress and reduced survival in women diagnosed with breast cancer, and could lead to new strategies to improve treatment outcomes.
Unal receives Orthopedic Research Society award
Jun. 15, 2017—Mustafa Unal, Ph.D., a postdoctoral research fellow at Vanderbilt University School of Medicine, has been selected by the Orthopedic Research Society to receive its 2017 Alice L. Jee Young Investigator Award for work that potentially will improve the clinical assessment of bone strength and quality.
Plasmin prevents muscle ‘hardening’ after injury: study
Dec. 8, 2016—Vanderbilt researchers have made the surprising discovery that the protease plasmin, known for its clot-busting role in the blood, protects soft tissue from turning to bone after severe injuries and certain orthopaedic surgeries.
Neurofibromin fine-tunes bone growth
May. 6, 2015—The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.
Inner ear keeps bones strong
Jan. 14, 2015—Alterations of the vestibular system - the part of our inner ear that controls balance - may contribute to bone loss related to both aging and space travel.
Novel treatment strengthens bones in genetic disease
Aug. 7, 2014—An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.
Factor impacts bone toughness
Jun. 16, 2014—The factor ATF4 has a role in the toughness of bone and its resistance to fracture, suggesting new therapeutic targets.
Neurotransmitter’s role in bone balance
Nov. 7, 2013—Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling.
Factor’s role in long bone development
Jul. 31, 2013—Insight into how the protein neurofibromin participates in the signaling pathway that produces the body’s long bones has implications for fracture healing in some patients.
