cancer biology Archives
Study identifies key regulator of melanoma development
Jun. 29, 2023—Vanderbilt investigators have revealed the mechanisms by which the chemokine receptor CXCR2, is associated with melanoma tumor formation and growth — a discovery that supports the continued development of drugs that inhibit the receptor’s activity.
Study finds inherited link to appendix cancer
Nov. 11, 2022—A Vanderbilt study is the first to show inherited risk factors for appendiceal cancer.
Nanoparticles boost anti-cancer immunity
Aug. 16, 2022—An ingenious targeted nanoparticle approach developed by Vanderbilt researchers reduced tumor burden in a model of ovarian cancer.
Cell-free breast cancer “biopsy”
Aug. 11, 2022—The circulating DNA that tumors release is a reliable metric of tumor genomics and can be used to monitor molecular changes in metastatic breast cancer.
Holowatyj named chair of scientific advisory board for ACPMP Research Foundation
Jul. 15, 2022—Vanderbilt's Andreana Holowatyj, PhD, MSCI, has been named the inaugural chair of the scientific advisory board for the Appendix Cancer Pseudomyxoma Peritonei Research Foundation.
IMPACT research grants to help underserved patients access clinical trials
May. 6, 2021—The Leukemia & Lymphoma Society (LLS) announced today the launch of IMPACT (Influential Medicine Providing Access to Clinical Trials) research grants to increase enrollment of individuals from underrepresented communities in clinical trials. Vanderbilt University Medical Center is leading one of the first three projects to receive IMPACT funding.
Study reveals distinct genomic landscape for young adults with appendiceal cancer
Dec. 17, 2020—The first study to compare molecular landscapes of early-onset and late-onset appendiceal cancer has revealed distinct non-silent mutations in the tumors of younger patients, setting the stage for the development of potential therapeutic advances for this rare disease.
Grant bolsters research on myelodysplastic syndromes
Aug. 1, 2019—Michael Savona, MD, has received a competitive grant to develop therapies for patients with myelodysplastic syndromes.
Protein loss promotes cell migration
Feb. 28, 2019—The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.
Breast cancer-killing RIG
Dec. 13, 2018—A compound that activates a virus-sensing receptor has potent therapeutic effects in a mouse model of breast cancer.
“Idling” cancer cells may return
Apr. 11, 2018—Vanderbilt investigators have discovered that cancer treatment induces an “idling” state for cells, which could promote resistance to treatment.
Radiation and pulmonary fibrosis
Nov. 15, 2017—To develop strategies for preventing radiation-induced lung fibrosis (scarring), Vanderbilt investigators are exploring the cell types and factors that contribute to the fibrotic response.
