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cancer biology Archives

Single-cell analysis of solid tumors

Dec. 12, 2016—A new method will make it possible to study solid tumors and healthy tissues using mass cytometry.

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Links between immune cells and metabolism explored

Nov. 10, 2016—At the intersection of immunology and metabolism is a burgeoning new field: immunometabolism. It’s an area where Vanderbilt has exceptional strengths, said Jeffrey Rathmell, Ph.D., Cornelius Vanderbilt Professor of Immunobiology.

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A DARPP role in gastric cancer

Nov. 3, 2016—Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies.

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EGF receptor found to regulate macrophage inflammation in gut

Oct. 13, 2016—Researchers at Vanderbilt University School of Medicine have uncovered a link between epidermal growth factor receptor (EGFR) signaling and the inflammatory response to bacterial infection in the gastrointestinal tract.

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Basic science, extraordinary impact

Oct. 6, 2016—The discoveries that can change the course of human health forever often begin in the tiniest places: in molecules and cells, at the most fundamental intersection of physics, chemistry and biology. Understanding how these cellular and molecular processes work is the focus of basic biomedical research at Vanderbilt.

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In search of new cancer targets

Sep. 9, 2016—Vanderbilt researchers developed a new algorithm to find clinically targetable gene rearrangements in cancers.

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Proliferative capacity of neuroblastoma

Aug. 31, 2016—The sphere-forming frequency of neuroblastoma cells is a measure of their proliferative capacity and could help guide treatment strategies for neuroblastoma.

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New breast cancer driver

Aug. 26, 2016—Vanderbilt investigators have demonstrated that a certain protein complex drives tumor progression in aggressive breast cancers.

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Lovly tapped to brief Congress on cancer research

Jun. 22, 2016—Christine Lovly, M.D., Ph.D., assistant professor of Medicine and Cancer Biology, has been selected to testify before members of Congress about the importance of cancer research, including early training programs for individuals interested in science.

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Pulmonary fibrosis culprits

Jun. 6, 2016—New findings identify isoketal-modified proteins as a previously unrecognized feature of pulmonary fibrosis and as a potential therapeutic target for this disease.

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Thompson’s Discovery Lecture

May. 12, 2016—Craig Thompson, M.D., president and CEO of Memorial Sloan Kettering Cancer Center, spoke about his lab’s research linking metabolism to stem cell maintenance during his recent Flexner Discovery Lecture.

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Current cancer drug discovery method flawed: VUMC study

May. 5, 2016—The primary method used to test compounds for anti-cancer activity in cells is flawed, Vanderbilt University researchers reported May 2 in Nature Methods.

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