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cancer biology Archives

Drug combos for glioblastoma

May. 3, 2016—Vanderbilt researchers have discovered that activation of a certain signaling pathway protects brain cancers from targeted therapies, suggesting that using therapeutics that block both pathways may be a promising treatment.

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An Argonaute’s voyage to cancer

Apr. 28, 2016—A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.”

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Cancer expert Thompson to deliver May 5 Flexner Discovery Lecture

Apr. 28, 2016—Craig Thompson, M.D., president and CEO of Memorial Sloan Kettering Cancer Center, will deliver the next Flexner Discovery Lecture on May 5.

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New role identified for p73 gene

Apr. 1, 2016—The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility.

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Melanoma response to immune therapy

Mar. 3, 2016—Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy.

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Combining treatments for melanoma

Feb. 18, 2016—Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients.

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Study identifies potential colon cancer biomarker

Feb. 11, 2016—A protein that suppresses a key cancer pathway in the colon may be a potential biomarker for colitis-associated tumors, researchers at Vanderbilt University Medical Center reported last month in the journal Gut.

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Overcoming lung cancer drug resistance

Feb. 10, 2016—Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients.

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New lead for ovarian cancer treatment

Dec. 10, 2015—Combining inhibitors of the BMP signaling pathway with standard chemotherapy drugs may overcome drug resistance in ovarian cancer.

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VICC’s Balko named a Susan G. Komen ‘Pink Tie Guy’

Dec. 10, 2015—Justin Balko, Pharm.D., Ph.D., assistant professor of Medicine and Cancer Biology, has been named a member of the 2016 class of Pink Tie Guys by the Greater Nashville Affiliate of Susan G. Komen, a nonprofit organization dedicated to breast cancer research and patient support.

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Stomach cancer cues

Aug. 6, 2015—Vanderbilt scientists have discovered a new molecular mechanism that promotes stomach cancer development, findings that could provide new opportunities for treatment.

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Targeting bone metastasis

Jul. 23, 2015—The rigidity of the bone extracellular matrix increases the ability of tumor cells to destroy bone, suggesting new targets for anticancer drug development.

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