cancer biology Archives
Drug combos for glioblastoma
May. 3, 2016—Vanderbilt researchers have discovered that activation of a certain signaling pathway protects brain cancers from targeted therapies, suggesting that using therapeutics that block both pathways may be a promising treatment.
An Argonaute’s voyage to cancer
Apr. 28, 2016—A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.”
Cancer expert Thompson to deliver May 5 Flexner Discovery Lecture
Apr. 28, 2016—Craig Thompson, M.D., president and CEO of Memorial Sloan Kettering Cancer Center, will deliver the next Flexner Discovery Lecture on May 5.
New role identified for p73 gene
Apr. 1, 2016—The p73 gene is required for the generation of cilia – hair-like projections on cells – findings that could have implications for the study of lung diseases and sterility.
Melanoma response to immune therapy
Mar. 3, 2016—Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy.
Combining treatments for melanoma
Feb. 18, 2016—Combining therapies for melanoma that induce cell senescence and that activate the immune response may improve outcomes for patients.
Study identifies potential colon cancer biomarker
Feb. 11, 2016—A protein that suppresses a key cancer pathway in the colon may be a potential biomarker for colitis-associated tumors, researchers at Vanderbilt University Medical Center reported last month in the journal Gut.
Overcoming lung cancer drug resistance
Feb. 10, 2016—Vanderbilt investigators have discovered a way to overcome the resistance of some lung cancers to certain targeted therapies, which could lead to more effective treatments for lung cancer patients.
New lead for ovarian cancer treatment
Dec. 10, 2015—Combining inhibitors of the BMP signaling pathway with standard chemotherapy drugs may overcome drug resistance in ovarian cancer.
VICC’s Balko named a Susan G. Komen ‘Pink Tie Guy’
Dec. 10, 2015—Justin Balko, Pharm.D., Ph.D., assistant professor of Medicine and Cancer Biology, has been named a member of the 2016 class of Pink Tie Guys by the Greater Nashville Affiliate of Susan G. Komen, a nonprofit organization dedicated to breast cancer research and patient support.
Stomach cancer cues
Aug. 6, 2015—Vanderbilt scientists have discovered a new molecular mechanism that promotes stomach cancer development, findings that could provide new opportunities for treatment.
Targeting bone metastasis
Jul. 23, 2015—The rigidity of the bone extracellular matrix increases the ability of tumor cells to destroy bone, suggesting new targets for anticancer drug development.
