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cancer biology Archives

Growth factor blockade targets breast tumors

Aug. 14, 2014—Inhibition of BMP growth factor signaling reduces breast tumor burden and metastasis.

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Novel treatment strengthens bones in genetic disease

Aug. 7, 2014—An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

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Drug discovery clues in network map

Aug. 5, 2014—Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies.

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Repair protein’s DNA recognition motif

May. 23, 2014—Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.

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Potential mechanism for myeloma drug’s variable toxicity

Apr. 30, 2014—A genetic variant is associated with toxicity of the chemotherapy drug melphalan, and could guide individualized dosing for the medication.

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Study links stem cell gene to prostate cancer susceptibility

Mar. 27, 2014—A gene on chromosome 8 — in a region of the genome linked to risk for many types of cancer — is particularly associated with prostate cancer susceptibility, Vanderbilt University researchers have found.

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New direction for treating lung cancer

Feb. 7, 2014—Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer.

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Cancer cells combine tools to increase invasiveness

Dec. 19, 2013—Two features of invasive cancer cells — invadopodia and exosomes — are linked together, Vanderbilt University investigators have discovered.

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Therapeutic target for gastric cancer

Dec. 12, 2013—A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.

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Therapeutic target for synovial sarcoma

Nov. 21, 2013—Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer.

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Molecular circuits in ovarian cancer

Nov. 13, 2013—Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer.

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VU study sheds new light on DNA replication

Nov. 7, 2013—David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes.

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Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

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