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cancer biology Archives

Molecular circuits in ovarian cancer

Nov. 13, 2013—Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer.

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VU study sheds new light on DNA replication

Nov. 7, 2013—David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes.

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Gene interactions and cavities

Sep. 30, 2013—Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay.

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Tumor factor spurs blood vessel growth

Aug. 26, 2013—A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

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Visualizing data on network ‘maps’

Jul. 25, 2013—The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification.

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Predicting cancer’s response to therapy

Jun. 24, 2013—Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding.

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Vanderbilt to host seventh international conference on tetraspanin scaffolding

Jun. 7, 2013—Experts from around the world will come to Vanderbilt June 18-21 for the seventh international summer research conference to discuss the role of tetraspanins and related membrane scaffolding proteins in biology and disease. Much of the communication that takes place between a cell and its environment is performed by transmembrane proteins. The availability and activity...

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Inner ear’s role in bone remodeling

May. 15, 2013—The inner ear system that senses gravity and movement plays a role in bone remodeling – a finding that has clinical implications for space travel and for patients with inner ear disorders.

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Dual-action enzyme protects esophagus

May. 9, 2013—An antioxidant enzyme also functions as a tumor suppressor to limit cancer development in the esophagus.

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Leukemia culprit’s cellular actions

Apr. 11, 2013—Overexpression of a gene that is a common culprit in leukemia induces stem cell-like features in T cells, which may enable the cells to become cancerous.

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Nobel laureate Hartwell set for Discovery Lecture

Apr. 4, 2013—Nobel laureate Lee Hartwell, Ph.D., will deliver the next Flexner Discovery Lecture on Thursday, April 11.

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Foundation lauds graduate student’s melanoma research

Mar. 28, 2013—Katherine Hutchinson, a third-year graduate student in Cancer Biology at Vanderbilt University, has won a $10,000 Research Scholar Award from the Joanna M. Nicolay Melanoma Foundation.

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