cancer biology Archives
New direction for treating lung cancer
Feb. 7, 2014—Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer.
Cancer cells combine tools to increase invasiveness
Dec. 19, 2013—Two features of invasive cancer cells — invadopodia and exosomes — are linked together, Vanderbilt University investigators have discovered.
Therapeutic target for gastric cancer
Dec. 12, 2013—A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.
Therapeutic target for synovial sarcoma
Nov. 21, 2013—Inhibitors of a signaling pathway that is critical to synovial sarcoma tumorigenesis may be useful treatments for this aggressive cancer.
Molecular circuits in ovarian cancer
Nov. 13, 2013—Vanderbilt researchers have used bioinformatics analysis of gene expression data to describe molecular “circuits” that drive ovarian cancer.
VU study sheds new light on DNA replication
Nov. 7, 2013—David Cortez, Ph.D., and his Vanderbilt colleagues report new findings that shed light on fundamental processes involved in DNA replication and have implications for cancer therapies that target these processes.
Gene interactions and cavities
Sep. 30, 2013—Vanderbilt researchers used existing genome-wide association study datasets to identify gene interactions that contribute to tooth decay.
Tumor factor spurs blood vessel growth
Aug. 26, 2013—A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.
Visualizing data on network ‘maps’
Jul. 25, 2013—The new web application NetGestalt will allow investigators to simultaneously visualize different types of data for the same gene – such as mutation, expression and modification.
Predicting cancer’s response to therapy
Jun. 24, 2013—Researchers are developing imaging methods to predict patient outcome early in the course of chemotherapy for breast cancer – to allow clinicians to adjust therapy for patients who are not responding.
Vanderbilt to host seventh international conference on tetraspanin scaffolding
Jun. 7, 2013—Experts from around the world will come to Vanderbilt June 18-21 for the seventh international summer research conference to discuss the role of tetraspanins and related membrane scaffolding proteins in biology and disease. Much of the communication that takes place between a cell and its environment is performed by transmembrane proteins. The availability and activity...
Inner ear’s role in bone remodeling
May. 15, 2013—The inner ear system that senses gravity and movement plays a role in bone remodeling – a finding that has clinical implications for space travel and for patients with inner ear disorders.