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cancer biology Archives

Brain tumor TIP reveals new target

Feb. 4, 2013—The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development.

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Do-it-yourself repair in the kidney

Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.

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A drug combo for ovarian cancer

Dec. 24, 2012—Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.

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Study tracks antioxidants’ role in prostate tumor growth

Nov. 15, 2012—Antioxidants promote cell growth in a mouse model of prostate cancer, Vanderbilt researchers report in the journal PLoS ONE. The findings provide insight into the recent controversy regarding antioxidants and prostate cancer prevention.

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Stomach bug alters tumor suppressor

Oct. 23, 2012—The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.

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Proteins help flip tumor’s invasive switch

Oct. 4, 2012—Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.

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Target acquired for aggressive tumor

Sep. 27, 2012—New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified.

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Cells with LIP eat their neighbors

Sep. 13, 2012—A transcription factor called LIP is capable of causing one cell to consume another.

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Enzyme counters stomach acid attack

Sep. 11, 2012—Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.

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Gene linked to familial prostate cancer

Aug. 23, 2012—A rare, inherited mutation confers an eightfold increased risk of prostate cancer, a recent study shows.

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Network approach yields glioblastoma clues

Aug. 9, 2012—MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor.

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On the hunt for bladder cancer factors

Jul. 26, 2012—A protein linked to aggressive bladder cancers could point to new strategies for treatment or prevention.

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Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

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