cancer biology Archives
New drugs a good BET for brain cancer
Mar. 20, 2013—A novel class of drugs that target “BET” proteins may have broad utility for treating genetically diverse brain tumors.
Linking oxygen, iron and red blood cells
Feb. 6, 2013—The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.
Brain tumor TIP reveals new target
Feb. 4, 2013—The protein TIP-1 appears to be a novel prognostic marker for glioblastoma and may be a good therapeutic target for disrupting tumor-driven blood vessel development.
Do-it-yourself repair in the kidney
Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.
A drug combo for ovarian cancer
Dec. 24, 2012—Combining another drug with platinum-based chemotherapies may be more effective against ovarian cancer.
Study tracks antioxidants’ role in prostate tumor growth
Nov. 15, 2012—Antioxidants promote cell growth in a mouse model of prostate cancer, Vanderbilt researchers report in the journal PLoS ONE. The findings provide insight into the recent controversy regarding antioxidants and prostate cancer prevention.
Stomach bug alters tumor suppressor
Oct. 23, 2012—The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.
Proteins help flip tumor’s invasive switch
Oct. 4, 2012—Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.
Target acquired for aggressive tumor
Sep. 27, 2012—New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified.
Cells with LIP eat their neighbors
Sep. 13, 2012—A transcription factor called LIP is capable of causing one cell to consume another.
Enzyme counters stomach acid attack
Sep. 11, 2012—Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.
Gene linked to familial prostate cancer
Aug. 23, 2012—A rare, inherited mutation confers an eightfold increased risk of prostate cancer, a recent study shows.
