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cancer biology Archives

Proteins help flip tumor’s invasive switch

Oct. 4, 2012—Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.

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Target acquired for aggressive tumor

Sep. 27, 2012—New therapeutic target for angiosarcoma – an aggressive, highly fatal tumor of the blood vessels – identified.

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Cells with LIP eat their neighbors

Sep. 13, 2012—A transcription factor called LIP is capable of causing one cell to consume another.

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Enzyme counters stomach acid attack

Sep. 11, 2012—Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.

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Gene linked to familial prostate cancer

Aug. 23, 2012—A rare, inherited mutation confers an eightfold increased risk of prostate cancer, a recent study shows.

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Network approach yields glioblastoma clues

Aug. 9, 2012—MicroRNA “regulatory networks” generated at Vanderbilt aid search for biomarkers and new drugs to treat glioblastoma, the most common and lethal primary brain tumor.

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On the hunt for bladder cancer factors

Jul. 26, 2012—A protein linked to aggressive bladder cancers could point to new strategies for treatment or prevention.

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Proteins guard against cancer spread

Jul. 24, 2012—Targeting immune system proteins may keep prostate cancer from spreading to bone.

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VU study finds stress fuels breast cancer metastasis to bone

Jul. 18, 2012—Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered.

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New drug mutes more melanomas

Apr. 26, 2012—An experimental melanoma drug may be beneficial for patients not eligible for targeted therapies.

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Factor sensitizes cancer to radiation

Apr. 6, 2012—Measuring levels of an enzyme in head and neck tumors may indicate how the tumor will respond to radiation therapy.

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Smoking stokes cells’ cancer capacity

Mar. 23, 2012—Cellular pathways altered by chronic exposure to cigarette smoke may reveal new biomarkers to assess smoking-induced lung cancer risk.

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