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cancer Archives

VUMC researchers find a way to ‘starve’ cancer

Jan. 16, 2018—Researchers at Vanderbilt University Medical Center (VUMC) have demonstrated for the first time that it is possible to starve a tumor and stop its growth with a newly discovered small compound that blocks uptake of the vital nutrient glutamine.

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Radiation and pulmonary fibrosis

Nov. 15, 2017—To develop strategies for preventing radiation-induced lung fibrosis (scarring), Vanderbilt investigators are exploring the cell types and factors that contribute to the fibrotic response.

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Boosting sarcoma cell death

Oct. 4, 2017—A compound identified at Vanderbilt represents a new lead for treating rare, aggressive childhood cancers called Ewing sarcomas.

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Study identifies protein’s role in chemotherapy resistance

Jul. 20, 2017—Researchers at Vanderbilt University Medical Center (VUMC) have discovered a protein that may lead to a new way to prevent resistance and improve outcomes for patients whose cancers have mutations in the tumor suppressor gene BRCA2.

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Genetics of lung cancer survival

Jun. 29, 2017—Vanderbilt investigators have conducted a first-of-its-kind genome-wide association study of lung cancer survival in African-Americans.

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STINGing combination for cancer

Jun. 19, 2017—A novel immunotherapy combination induced remarkable regression of tumors in a mouse model of head and neck cancer.

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Repriming replication roadblocks

Jun. 12, 2017—New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

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Oxidative stress in tumors

May. 18, 2017—Vanderbilt investigators have developed a new method for measuring oxidative stress in human tumors, which provides insight into cancer development.

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Richmond to speak at national VA research conference on cancer immunotherapy

May. 11, 2017—Vanderbilt University cancer researcher Ann Richmond, Ph.D., 2016 recipient of one of the highest honors for scientific achievement bestowed by the U.S. Department of Veterans Affairs, will be a keynote speaker during a national VA research conference next week at Vanderbilt University School of Medicine.

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My Southern Health: The ABCDEs of caring for the heart during cancer treatment—and beyond

Feb. 28, 2017—People who have dealt with cancer may also need to take special care of their hearts. Here’s how.

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COX-2 ‘conjugate’ may slow growth of some tumors: study

Jan. 19, 2017—More than a decade after the anti-inflammatory drugs Vioxx and Bextra were pulled from the market because of a heightened risk of heart attack and stroke in some patients, COX-2 inhibitors may be on the verge of a comeback, this time as anti-cancer agents.

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Softening tumor tissue could aid cancer treatments

Jan. 16, 2017—Tumors cause the intracellular material surrounding them to stiffen. Softening this protective layer could make existing cancer treatments more effective, according to new research.

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