cardiovascular disease Archives

Peptides promote AFib arrhythmia

Apr. 11, 2022—Peptide oligomers have detrimental metabolic effects and cause pro-arrhythmic electrophysiological changes in heart atria, suggesting they may contribute to atrial fibrillation.

Study finds World Trade Center responders at higher risk for blood cancer-associated mutations

Mar. 7, 2022—A study by Vanderbilt and New York City researchers found that 9/11 first responders to the World Trade Center have increased levels of mutations that escalate their risk for blood cancers or cardiovascular disease

PHOTO: Members of the supermere discovery team include (front row from left) Qi Liu, PhD, Robert Coffey, MD, Qin Zhang, PhD, and (back row from left) James Higginbotham, PhD; Dennis Jeppesen, PhD; and Jeffrey Franklin, PhD. (hoto by Erin O. Smith)

“Supermeres” may carry clues to cancer, Alzheimer’s disease and COVID-19

Dec. 10, 2021—Vanderbilt researchers have discovered a nanoparticle released from cells, called a “supermere,” which contains enzymes, proteins and RNA associated with multiple cancers, cardiovascular disease, Alzheimer’s disease and even COVID-19.

Officials cut the ribbon at last week’s dedication of VUMC’s new hybrid operating rooms.

VUMC debuts two new state-of-the-art hybrid operating rooms

Nov. 2, 2021—Vanderbilt is opening two of the newest generation of hybrid operating rooms, which each combine a traditional operating room with the latest advanced imaging equipment.

Potential protection from atherosclerosis

Aug. 19, 2021—Vanderbilt researchers have discovered a potential way to reduce atherosclerosis: blocking the modification of an HDL-associated enzyme by reactive molecules called isolevuglandins.

Mariana Byndloss, DVM, PhD, Woongjae Yoo, PhD, and colleagues are studying how a high-fat diet may contribute to heart disease. (Photo taken prior to revised masking guidelines.)

Study reveals missing link between high-fat diet, microbiota and heart disease

Aug. 12, 2021—A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

Wanjalla honored by Doris Duke Foundation

Aug. 12, 2021—Celestine Wanjalla, MD, PhD, assistant professor of Medicine in the Division of Infectious Diseases, is among 17 recipients of the Doris Duke Charitable Foundation 2021 Clinical Scientist Development Award.

Vitamin D impact on disease biomarkers

Aug. 10, 2021—In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease.

Probing statin-associated diseases with genetics

Jul. 12, 2021—Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.

VUMC is pacesetter for national aspirin study

May. 20, 2021—According to an innovative large-scale clinical trial reported last week in the New England Journal of Medicine, a single daily baby aspirin (81 mg) or a single daily adult aspirin (325 mg) are equally safe and effective for prevention of adverse cardiovascular events for patients with established atherosclerotic cardiovascular disease.

Salt, immune cells and hypertension

Aug. 20, 2020—Excess dietary salt activates immune cells to induce inflammation and hypertension, supporting current recommendations for low sodium consumption.

Soy food, metabolism and the microbiome

Jul. 27, 2020—Consumption of soy foods may shape the microbiome and protect against hypertension only in individuals with soy-responsive microbiota, Vanderbilt researchers have discovered.