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cell death Archives

Study finds that regulatory protein prevents signaling that triggers cell death

May. 6, 2021—A protein implicated in neurodegenerative diseases including amyotrophic lateral sclerosis prevents the activation of an innate immune response that leads to cell death, Vanderbilt researchers have discovered.

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One-two punch for cancer

Mar. 5, 2020—A drug combination effectively killed aggressive blood cancers in cell and animal models; now it’s being tested in patients.

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Cell death pathway implicated in bone marrow failure

Jan. 31, 2019—Vanderbilt investigators have linked a specific form of programmed cell death to myelodysplastic syndrome, a type of bone marrow failure.

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PET probe detects dying tumor cells

May. 8, 2014—A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine.

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Early cell death in MS

Oct. 2, 2013—Death of oligodendrocytes, the cells that make myelin, appears to be an early event in the development of multiple sclerosis.

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Nuclear shield against cell death

Aug. 8, 2013—The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.

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Probing roles of a cell death protein

Jul. 17, 2013—Vanderbilt researchers have discovered new roles for a protein involved in cell death processes that are activated to prevent tumor-causing DNA mutations.

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Bid protein guards blood cells against stress

Oct. 25, 2012—A protein normally known to promote cell death found to encourage survival of blood forming cells.

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Cells with LIP eat their neighbors

Sep. 13, 2012—A transcription factor called LIP is capable of causing one cell to consume another.

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