Cell Reports Archives
Probing pathogen antibiotic resistance
Sep. 17, 2020—Understanding how bacteria evolve resistance to antibiotics and host stresses could guide the development of more effective antimicrobial therapeutics.
New clue to Alzheimer’s disease
Sep. 3, 2020—Combining studies of genetically diverse mouse populations and human data led to the identification of a gene associated with cognitive decline and brain changes in Alzheimer’s disease.
The importance of estrogen cycles
Aug. 6, 2020—Deborah Lannigan and colleagues identify a key regulator of the estrogen receptor and suggest that its downregulation by oral contraceptives may increase oxidative stress and DNA damage, a common cause of cancer.
New study supports remdesivir as COVID-19 treatment
Jul. 9, 2020—This week researchers at Vanderbilt University Medical Center (VUMC), the University of North Carolina at Chapel Hill and Gilead Sciences reported that remdesivir potently inhibited SARS-CoV-2, the virus which causes COVID-19, in human lung cell cultures and that it improved lung function in mice infected with the virus.
Probing DNA damage repair
Jun. 18, 2020—After discovering a new mechanism for DNA damage repair last year, Vanderbilt biochemists now provide direct evidence for how it works.
Studying cells in reduced dimensions
Jun. 18, 2020—Vanderbilt cell biologists have developed an unbiased, quantitative framework for evaluating single-cell data.
‘Tuning’ cell shape for division
Apr. 16, 2020—Dylan Burnette and colleagues have discovered that two forms of the molecular motor protein myosin have distinct roles in regulating cell shape during cell division.
Completing DNA synthesis
Oct. 21, 2019—James Dewar and colleagues have identified a role for the enzyme topoisomerase II in reducing replication errors during the final stage of DNA synthesis.
Zebrafish aid effort to regenerate damaged retinas
Sep. 5, 2019—According to a new study, the tiny zebrafish may hold the secret to regenerating damaged retinas in humans.
A “rheostat” for cancer signals
Aug. 27, 2019—Jason MacGurn and colleagues have characterized a “rheostat” that sets WNT pathway signaling in breast cancer cells.
How bugs overcome host defenses
Apr. 11, 2019—Vanderbilt researchers led by Eric Skaar are probing the mechanisms bacteria use when faced with nutrient starvation — a host defense strategy called “nutritional immunity.”
Destructive ‘telegrams’ in asthma
Jan. 31, 2019—Vanderbilt investigators have discovered that certain microRNAs — "telegram"-like signals — increase after the induction of allergic airway inflammation.
