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Charlotte and Donald Test Fund Archives

White matter and schizophrenia

Sep. 2, 2021—Patients with schizophrenia have functional changes in the white matter of the brain, Vanderbilt researchers have discovered, which may contribute to impaired working memory and processing speed.

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Pinpointing brain changes in psychosis

Oct. 1, 2020—Specific regions of the thalamus — a central brain region — are smaller in adults with psychotic disorders and youth at risk for psychotic disorders and are associated with cognitive impairment.

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A connection to schizophrenia

Jun. 23, 2020—The insula, a small region of the brain involved in diverse brain functions had widespread dysconnectivity in schizophrenia, Vanderbilt researchers found.

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Relational memory in early psychosis

Sep. 10, 2019—Studies of relational memory function may reveal novel mechanisms for therapeutic intervention for patients in the early stages of psychosis.

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Working memory in psychotic disorders

Jul. 11, 2019—Functional MRI studies have revealed that targeting activation of certain brain regions may improve working memory and cognition in psychotic disorders.

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Early detection of schizophrenia

Jun. 24, 2019—Inhibited temperament — a tendency to respond to novelty with wariness, fear or caution — may be a risk factor for schizophrenia that could be targeted for preventative interventions.

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