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chemotherapy Archives

Breast cancer biomarkers of response

Jun. 16, 2022—Vanderbilt researchers have identified blood-based biomarkers associated with complete responses to neoadjuvant chemotherapy in patients with breast cancer.

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Improving care for gynecologic cancer

Mar. 15, 2022—To reduce risk of deep vein thrombosis in patients being treated for gynecologic cancer, Vanderbilt researchers recommend that providers use Khorana scores and provide prophylactic treatment according to clinical guidelines.

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Mood and cognition after chemotherapy

Jul. 26, 2021—Validation of cognitive complaints appears to improve mood in patients with persistent chemotherapy-cognitive impairment, Vanderbilt researchers report.

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Researchers discover that protein switches functions to regulate DNA replication

Jul. 22, 2021—Vanderbilt biochemists have discovered what the DNA damage response protein RADX does — and how it does it.

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Chemo for cancer lowers dementia risk

Mar. 22, 2021—Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people.

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Correctly copying DNA

Mar. 14, 2019—A precise understanding of how the enzyme topoisomerase II cuts DNA could lead to better anti-cancer therapies.

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Grant enhances study of new chemotherapy targets

Oct. 18, 2018—Vanderbilt chemists have been awarded $7.2 million over the next five years from the National Cancer Institute to lead an initiative to better understand how a combination chemotherapy for breast cancer targets DNA.

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Cochran celebrates cancer treatment’s end in style

Oct. 4, 2018—Singer Anita Cochran had famous friends in the room when she celebrated her last cancer treatment, but the person with her who mattered the most was her 89-year-old father.

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A new mode of DNA repair

Apr. 14, 2017—Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.

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Chemo better option following pancreatic cancer surgery: study

Feb. 25, 2016—A multicenter study led by Vanderbilt University Medical Center (VUMC) investigators found that pancreatic cancer patients who underwent surgery and received chemotherapy lived longer and had fewer cancer recurrences in other parts of the body than patients who also received chemoradiation therapy.

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New lead for ovarian cancer treatment

Dec. 10, 2015—Combining inhibitors of the BMP signaling pathway with standard chemotherapy drugs may overcome drug resistance in ovarian cancer.

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Hach shows age not always a barrier to cancer therapy

Sep. 3, 2015—Phila Hach recently celebrated her 89th birthday and she has had much to celebrate over the years.

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