cholesterol Archives
Reminders for clinicians improve prescribing for high cholesterol
Mar. 23, 2023—A Vanderbilt study found that automated targeted reminders for clinicians helped increase prescribing of high intensity statins for patients with various atherosclerotic cardiovascular disease diagnoses, including coronary or peripheral artery disease and ischemic stroke.
A new view of a cholesterol carrier
Feb. 7, 2023—Vanderbilt researchers developed a novel method to measure small RNAs carried by HDL and demonstrated that these molecules circulate in greater concentrations than previously believed and are likely to contribute to communication between immune cells.
Study suggests new mechanism for lipid transporter
Sep. 15, 2022—A new model suggests that a protein involved in the generation of high-density lipoprotein (HDL) works differently than previously thought.
Probing statin-associated diseases with genetics
Jul. 12, 2021—Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.
NIH grant bolsters research on heart disease, cholesterol
Jan. 21, 2021—Thanks to major funding from the National Institutes of Health (NIH), researchers at Vanderbilt University Medical Center have made major inroads in understanding how high-density lipoprotein (HDL), commonly known as good cholesterol, in some cases may actually contribute to the development of atherosclerosis.
A new contributor to atherosclerosis
Jan. 27, 2020—Sean Davies and colleagues are exploring lipid aldehydes produced during oxidative stress and their contribution to HDL dysfunction and atherosclerosis.
All-in-one pill helps reduce blood pressure, cholesterol
Sep. 19, 2019—A single pill containing low doses of three medications to treat high blood pressure and one to lower cholesterol reduced the estimated risk of cardiovascular disease by 25%, according to a VUMC study.
Obesity negates beneficial drug effects
Nov. 8, 2018—A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.
Scavengers “protect” HDL
Jun. 29, 2018—Jun. 29, 2018—Lipid molecules that bind to HDL can modify its function — and blocking that modification can protect HDL and potentially lower the risk of atherosclerosis and heart disease.
Oxidative stress on the brain
Aug. 23, 2017—Vanderbilt investigators have discovered that oxidative damage may play an important role in the development of a rare cholesterol synthesis disease and in the behavioral changes of autism spectrum disorders.
VU team explores new cholesterol processing pathway
Apr. 23, 2015—A zebrafish model of a rare genetic disease has revealed an unexpected regulatory pathway for cholesterol absorption and processing.
Kidney disease impacts HDL function
Feb. 11, 2015—Chronic kidney disease impairs the protective functions of HDL, Vanderbilt researchers report this month.
