Circulation Research Archives
Study sheds light on the development of inflammation, high blood pressure and resulting kidney damage
Oct. 20, 2022—by Bill Snyder Researchers at Vanderbilt University Medical Center have found that the change in a single letter of the genetic code promotes, in a mouse model, the development of inflammation, high blood pressure and resulting kidney damage. Their findings, featured Oct. 14 on the cover of Circulation Research, suggest that targeting inflammatory cytokines, signaling...
Researchers discover how salt increases blood pressure
Aug. 17, 2022—A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune cells contributes to salt-sensitive hypertension.
High blood pressure genes improve heart surgery survival in children
Mar. 24, 2022—Vanderbilt researchers have found that children with a genetic makeup that predicts high blood pressure as adults are more likely to survive congenital heart defect repair surgery.
Vanderbilt study suggests way to prevent rare lung disease
Nov. 15, 2018—Research by Vanderbilt scientists suggests that it may be possible to prevent or even reverse pulmonary arterial hypertension, a rare, progressive disease characterized by narrowing of and high blood pressure in the small arteries of the lungs.
Going after the ‘heart attack gremlin’
Sep. 8, 2016—A protein called Gremlin 2 controls the extent of inflammation after heart attack and may be a good therapeutic target.
New method aids heart disease studies, drug discovery efforts
Jan. 14, 2016—A team of Vanderbilt investigators developed a new method for rapidly generating heart muscle cells from stem cells.
Heart repair factor
Sep. 17, 2015—A signaling factor called Wnt10b is a novel target for optimizing cardiac repair after a heart attack.
