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collagen Archives

Potential new cancer target

Jun. 4, 2020—Vanderbilt researchers have discovered the involvement of a certain type of adenosine receptor in mediating signaling that supports tumor growth and metastasis.

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Vanderbilt-led team discovers new genetic disease and defines underlying mechanism

Jan. 13, 2020—An international research team has discovered a new genetic syndrome caused by mutation of a single gene and named it CATIFA, an acronym for its core symptoms.

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New window on fibrosis

Aug. 8, 2019—A previously unrecognized role for a cell surface receptor may open new therapeutic options for the treatment of fibrotic diseases.

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Building the basement membrane

Nov. 21, 2016—Vanderbilt researchers have discovered steps in the regulation of a key enzyme that builds the basement membrane, a structure that undergirds nearly all animal tissues.

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How to build a basement

Sep. 9, 2015—Understanding the action of a certain enzyme will shed light on basement membrane function, and on disorders ranging from diabetic kidney disease to cancer.

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Molecular ‘chat’ holds kidney fibrosis clues

Jul. 10, 2014—A novel molecular “conversation” regulates kidney fibrosis – the final result of end-stage chronic kidney disease – suggesting new treatment options for this currently irreversible process.

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Recent Stories from VUMC News and Communications Publications

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