colon cancer Archives
Probing the tumor microenvironment
Jul. 12, 2022—Vanderbilt researchers used single-cell sequencing, imaging, and computational approaches to characterize the colonic tumor microenvironment, providing important insights to the components that play roles in colorectal tumor pathogenesis.
Martin shares colorectal cancer story, urges early detection
Mar. 9, 2022—Vanderbilt Wilson County Hospital's Lori Martin uses her own experiences to educate patients about the importance of early detection of colorectal cancer.
‘DNA’ podcast Season 2 explores COVID, science and trust in communities
Aug. 23, 2021—Listen to Episode 1, Blueprint for a Pandemic-Ready Society, and subscribe on your favorite platform. The first episode of the second season of Vanderbilt University Medical Center’s original podcast series, Vanderbilt Health DNA: Discoveries in Action, tackles bold questions and issues pushed to the surface by COVID-19. This season, the award-winning 10-episode series delves into...
Vitamin D activation and cancer risk
Jan. 7, 2021—Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women.
V Scholar Award to support Byndloss’ cancer research
Nov. 18, 2020—Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology, has received a V Scholar Award to support her studies of the links between obesity, the gut microbiome and colorectal cancer.
New markers of colorectal cancer risk
Oct. 29, 2020—Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo.
Blocking tumor ‘signals’ and ‘fuel’
Aug. 25, 2020—Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients.
Research team awarded $9 million to study extracellular RNA in colorectal cancer
Apr. 9, 2020—The NCI program project grant is supporting multiple projects that aim to define fundamental biological principles about extracellular RNA signaling and the development and aggressiveness of colorectal cancer, the second leading cause of cancer death in the United States.
Meat intake and colorectal polyps
Mar. 9, 2020—Red and processed meat intakes are strongly associated with increased risk of sessile serrated polyps, which are not as well studied as conventional adenomas.
Protein’s role in inflammation-related cancer studied
Aug. 15, 2019—Investigators are exploring the molecular mechanisms behind the association of chronic inflammation and colon cancer.
Protein loss promotes cell migration
Feb. 28, 2019—The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.
SMAD4 clue to colon cancer
Jul. 2, 2018—Loss of a gene that is part of the TGF-beta signaling pathway increased inflammation in the colon and was observed in half of human colitis-associated cancers.