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colorectal cancer Archives

Comprehensive framework outlined for addressing early-onset colorectal cancer research

Jan. 25, 2022—New research from Vanderbilt sets a comprehensive framework for addressing research challenges and patient needs for people under 50 with colorectal cancer.

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Study sets framework for precision surveillance of colorectal cancer

Dec. 14, 2021—Vanderbilt research has revealed some of the mechanisms by which polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision medicine.

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CRISPR screen identifies new anti-inflammatory drug target

Nov. 11, 2021—A novel CRISPR screen developed by Vanderbilt researchers identified a promising new target for anti-inflammatory therapeutics.

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People at high genetic risk for colorectal cancer benefit more from lifestyle changes

May. 13, 2021—People with a high polygenic risk score for colorectal cancer could benefit more at preventing the disease by leading healthy lifestyles than those at lower genetic risk, according to a study by Vanderbilt researchers published in the April issue of The American Journal of Clinical Nutrition.

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Chemo for cancer lowers dementia risk

Mar. 22, 2021—Cancer chemotherapy lowered risk of Alzheimer’s disease and other neurocognitive disorders that disproportionately affect older people.

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Vitamin D activation and cancer risk

Jan. 7, 2021—Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women.

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Hot spots identified for colorectal cancer mortality rates among young women

Nov. 23, 2020—Women diagnosed with early-onset colorectal cancer have a greater risk of dying from the disease depending upon their county of residence, according to a study published in Clinical and Translational Gastroenterology.

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V Scholar Award to support Byndloss’ cancer research

Nov. 18, 2020—Mariana Byndloss, DVM, PhD, assistant professor of Pathology, Microbiology and Immunology, has received a V Scholar Award to support her studies of the links between obesity, the gut microbiome and colorectal cancer.

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New drug for metastatic colorectal cancer enters phase 3 trial

Nov. 18, 2020—A new therapy for metastatic colorectal cancer that has been granted fast track designation by the U.S. Food and Drug Administration is being tested in a phase 3 clinical trial at Vanderbilt-Ingram Cancer Center.

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New markers of colorectal cancer risk

Oct. 29, 2020—Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo.

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Preserving gut mucus architecture

Oct. 20, 2020—A new method that keeps microbes and gut cells together will be useful for studies of complex host-microbe interactions and for analysis of clinical specimens.

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Blocking tumor ‘signals’ and ‘fuel’

Aug. 25, 2020—Combining two drugs reduced colorectal cancer cell growth in vitro and in an animal model, suggesting the combination may be a promising treatment for patients.

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