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Critical Illness Brain Dysfunction and Survivorship Center Archives

Reduced exercise capacity in ICU survivors

Sep. 22, 2022—ICU survivors who have impaired exercise capacity months after discharge may have damaged muscle mitochondria — the energy powerhouses of the cell, Vanderbilt researchers propose.

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Team helps patients battle post-COVID cognitive issues

Mar. 30, 2022—Jane Stories is one of many COVID-19 patients still plagued by debilitating symptoms that include achy muscles, anxiety, depression, panic attacks and cognitive impairment.

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Vanderbilt, Zambia researchers find delirium in hospitalized patients linked to mortality, disability in Sub-Saharan Africa

Feb. 11, 2021—Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE.

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Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients

Jan. 8, 2021—COVID-19 patients admitted to intensive care in the early months of the pandemic were subject to a significantly higher burden of delirium and coma than is typically found in patients with acute respiratory failure. Choice of sedative medications and curbs on family visitation played a role in increasing acute brain dysfunction for these patients.

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New center formed to treat, study ICU delirium, dementia

Oct. 4, 2018—Millions of patients in intensive care units each year develop delirium during their hospitalization and often leave the hospital with cognitive deficits similar to those suffering from traumatic brain injury or mild Alzheimer’s disease.

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