Crohn’s disease Archives
Vanderbilt researchers discover how gut inflammation leads to bone loss
Aug. 25, 2022—Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss.
Potential biomarker for IBD severity, cancer risk identified
Feb. 4, 2021—A selenium transport protein produced in the colon may be a novel biomarker for assessing disease severity and cancer risk in patients with inflammatory bowel disease.
Grant spurs effort to map biology of Crohn’s disease
Nov. 20, 2019—VUMC has been awarded a three-year, $3 million grant to map — in unprecedented detail — the biology of Crohn’s disease.
New treatment for Crohn’s disease
Mar. 22, 2016—A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease.
Study explores protein’s role in inflammation-associated cancer
Jul. 23, 2015—An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.
Film explores girl’s bowel transplant surgery journey
Apr. 9, 2015—A documentary to be screened at this year’s Nashville Film Festival will give audiences the opportunity to experience the life of a vivacious young woman making the biggest decision of her life: whether to risk rare and complicated surgery with the potential to radically change her life.
Partnership aims to boost Crohn’s disease research participation
Jan. 29, 2015—ResearchMatch, the nationwide online medical research volunteer recruitment and engagement service hosted by Vanderbilt University Medical Center, has announced a partnership with the Crohn’s & Colitis Foundation of America (CCFA), a volunteer-driven organization dedicated to curing Crohn’s disease and ulcerative colitis.
Increased cell permeability may protect from colitis
Apr. 25, 2014—Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation.
Plant compound quells inflammation
Apr. 6, 2012—Berberine, an herbal remedy for diarrhea and intestinal parasites, may be an effective treatment for gastrointestinal inflammatory diseases.
