Department of Defense Archives
Treating kidney injury before it happens
May. 23, 2023—Pretreatment of an animal model with a novel compound called PHAD reduced kidney injury, suggesting it may be a good candidate for preventing kidney injury in surgical patients.
Breast cancer genetics: new insights
Feb. 16, 2023—Largest genetic study of breast cancer to date identifies 222 genetic risk loci, 137 genes and multiple signaling pathways associated with risk, providing important new insights.
Novel lung cancer biomarker
Jan. 9, 2023—Autoantibodies against the p53 tumor suppressor protein may be a novel biomarker for identifying people, especially African Americans, at high risk for lung cancer.
Vanderbilt researchers discover how gut inflammation leads to bone loss
Aug. 25, 2022—Gastrointestinal inflammation, such as occurs in inflammatory bowel disease, triggers the expansion of a population of “bone-eating” cells, leading to bone loss.
Breast cancer biomarkers of response
Jun. 16, 2022—Vanderbilt researchers have identified blood-based biomarkers associated with complete responses to neoadjuvant chemotherapy in patients with breast cancer.
Diabetes, cardiovascular drug targets
May. 24, 2022—Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.
VU, VUMC research funding surpasses $1 billion
Apr. 6, 2022—Vanderbilt University and Vanderbilt University Medical Center received more than $1 billion in research funding awarded from external organizations in 2021.
Study sets framework for precision surveillance of colorectal cancer
Dec. 14, 2021—Vanderbilt research has revealed some of the mechanisms by which polyps develop into colorectal cancer, setting the framework for improved surveillance for the cancer utilizing precision medicine.
Temperature, newts and a skin-eating fungus
Mar. 8, 2021—Salamanders are more sensitive to a skin-eating fungus at colder temperatures, pointing to locations of North America where pathogen invasion is most likely.
Imaging guidance for nerve repair
Feb. 9, 2021—A noninvasive, quantitative MRI method could be used after surgical repair of traumatic peripheral nerve injury to help clinicians make decisions about whether additional surgical interventions are needed.
Possible COVID-19 “decoy”
Oct. 15, 2020—It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection.
Antibodies eye Pacific Island “fever”
May. 14, 2020—Vanderbilt Vaccine Center team isolates monoclonal antibodies against Ross River virus, which causes rash, fever and debilitating muscle and joint pain lasting three to six months.