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Department of Pharmacology Archives

Atrial disease and hypertension links

Dec. 18, 2014—New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.

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Bacterial secretion machinery: 3-D view

Dec. 11, 2014—New structural findings reveal how "gatekeeper" proteins participate in the secretion systems bacteria use to infect host cells.

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Protein implicated in atherosclerosis

Nov. 25, 2014—Vanderbilt researchers have discovered a new target for the prevention of atherosclerotic plaque development and cardiovascular disease.

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Nobel laureate sheds light on immune response system

Oct. 9, 2014—Peter Doherty, Ph.D., had some advice for young scientists at last week’s Flexner Discovery Lecture. The way to win a Nobel Prize, he said, “is to make a very big discovery first.”

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Seizure mutation impairs receptor

Sep. 30, 2014—Defects in the production of certain receptors are linked to the pathogenesis of genetic epilepsies and fever-induced seizures.

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Doherty set for next Discovery Lecture

Sep. 25, 2014—Nobel laureate Peter Doherty, Ph.D., who discovered how the immune system recognizes virus-infected cells, will deliver the next Flexner Discovery Lecture on Thursday, Oct. 2.

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Schizophrenia ‘switches’ discovered

Sep. 12, 2014—Drugs developed at Vanderbilt could provide a new way to treat schizophrenia in a personalized way.

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Bone healing therapy for NF1 fractures

Sep. 11, 2014—A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1.

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Novel treatment strengthens bones in genetic disease

Aug. 7, 2014—An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

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Pharmacology reached new heights on Hamm’s watch

Jun. 12, 2014—During her 13-year tenure as chair of Vanderbilt University’s Department of Pharmacology, Heidi Hamm, Ph.D., bolstered its international reputation, attracted 18 new faculty members and helped take it in new directions, such as drug discovery.

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Channel drug restores glucose balance

Apr. 16, 2014—A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis.

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E-records shed light on drug response

Mar. 31, 2014—Electronic medical records linked to DNA biobanks are a valid resource for defining and understanding the genetic factors that contribute to drug response.

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