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Department of Veterans Affairs Archives

Inflammatory driver of obesity

Aug. 25, 2022—Blocking the EGF receptor signaling pathway in immune system macrophages represents a new target for improving insulin resistance in people with obesity.

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Researchers discover how salt increases blood pressure

Aug. 17, 2022—A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune cells contributes to salt-sensitive hypertension.

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Diabetes, cardiovascular drug targets

May. 24, 2022—Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

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Computer eyeballs graft-vs-host disease

Apr. 7, 2022—A machine learning algorithm identified areas of skin affected by chronic graft-versus-host disease on par with clinicians, opening the door to streamlining and standardizing this measure of patient response to therapy.

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Invasive strep can defy zinc toxicity

Feb. 28, 2022—Vanderbilt researchers find that invasive Group B Streptococcus strains, a significant risk to pregnant patients and infants, can grow in presence of toxic zinc levels.

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Melanoma treatment response

Feb. 24, 2022—Targeting the interaction between melanoma and immune cells could improve responses to targeted cancer therapies, Vanderbilt researchers found.

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Gene variants increase risk of kidney failure in veterans of African ancestry with COVID-19: study

Feb. 10, 2022—Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, possibly explaining some health disparities associated with COVID-19.

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Accelerating podocyte production

Feb. 1, 2022—A new method developed by Vanderbilt researchers to generate kidney cells from stem cells offers a faster and less expensive way to make these valuable tools for studying kidney diseases.

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H. pylori, lipid loss and stomach cancer

Jan. 17, 2022—H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered.

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The role of integrins in kidney “integrity”

Jan. 13, 2022—Receptors called integrins play a critical role in maintaining the structure of the kidney, Vanderbilt researchers have discovered.

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New way to bEET insulin resistance

Nov. 11, 2021—Signaling molecules called EETs could improve insulin resistance, a primary risk factor for Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

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Study finds higher deaths among veterans in 2020, but less than general population

Nov. 9, 2021—  by Jake Lowary More U.S. veterans died in 2020 than in prior years, but the increase was less than the increase in the general population, a new study of Veterans Health Administration (VA) data by researchers at Vanderbilt University Medical Center (VUMC) and Boston University (BU) finds. Overall, the study, published in The Lancet...

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