Department of Veterans Affairs Archives
VUMC study sheds light on gastric cancer development
Jan. 16, 2020—VUMC researchers have created the world’s first laboratory model of precancerous changes in the lining of the stomach, a scientific tour de force that is helping to unlock the mysteries of gastric cancer development.
Bone matrix changes during aging
Jan. 10, 2020—Changes to the bone matrix that occur during aging may point to novel targets for treating osteoporosis.
Structural views of a C. diff toxin
Jan. 10, 2020—D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.
Endotoxin shock protector
Nov. 5, 2019—A novel tool developed by Vanderbilt scientists protects animals from endotoxin shock and can be used for mechanistic analyses of inflammation due to microbial and other insults.
Acute kidney injury recovery time impacts future risk
Oct. 31, 2019—Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients.
A new regulator of B cell development
Oct. 8, 2019—New findings establish a role for the pro-inflammatory molecule IL-33 in the early development of antibody-producing B cells.
A step toward gastric cancer
Oct. 3, 2019—New research findings provide insight into the detrimental events that develop in response to H. pylori infection.
Diabetes drug study explores cardiovascular risks for patients with kidney disease
Oct. 3, 2019—An observational study using medical record information from nearly 50,000 U.S. military veterans sheds new light on which drugs are best for patients with Type 2 diabetes and one of its common complications, kidney disease.
Study shines light on architecture of kidney disease
Sep. 25, 2019—A study of 280,000 U.S. veterans, including 56,000 African Americans, has identified in greater detail than ever before the genetic architecture of kidney function and chronic kidney disease (CKD), according to researchers at Vanderbilt University Medical Center and their colleagues.
Pancreatic cancer clue
Aug. 12, 2019—Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer.
Sex differences in kidney injury
Jul. 25, 2019—Men are more susceptible to progressive kidney disease than women; new VUMC studies point to differences in the expression and activation of the EGF receptor.
A new antibiotic’s mechanism of action
Apr. 25, 2019—Vanderbilt investigators have characterized how a new first-in-class antibacterial drug works, which will guide the development of additional compounds that overcome antibacterial resistance.
