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drug abuse Archives

Histamine circuits in brain reward center

Oct. 29, 2020—Histamine — commonly associated with allergies — also has a signaling role in the brain’s reward center and may offer a novel target for treating addiction.

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Investigators find that bile acids reduce cocaine reward

Aug. 30, 2018—Bile acids — gut compounds that aid in the digestion of dietary fats — reduce the desire for cocaine, according to a new study by researchers at Vanderbilt and the University of Alabama at Birmingham.

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Shaping reward circuits

May. 18, 2018—Using techniques to control and monitor the activities of individual neurons, Vanderbilt investigators are probing the brain’s reward circuitry.

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An immune regulator of addiction

Aug. 4, 2017—Although drug addiction is classically studied in a neuron-centric way, Vanderbilt researchers have discovered that the immune system also plays a critical role.

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Probing drug abuse circuitry

Nov. 4, 2016—Vanderbilt researchers have identified cocaine-induced modifications at specific neuronal connections, which could aid the development of new therapies for substance abuse disorders.

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Diabetes drugs may ease addiction

Jul. 18, 2016—Drugs that are being used clinically to treat obesity and diabetes may also have a role in treating drug abuse.

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