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Edward P Evans Foundation Archives

Blood cancer progression

Aug. 29, 2022—Vanderbilt researchers used single-cell technologies to explore the accumulation of mutations during blood cancer progression, which could help identify strategies for preventing leukemia before it occurs.

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Impaired neutrophils in autoimmunity

Jan. 27, 2022—Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity.

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Caught in a web: study reveals that immune cells cooperate to trap and kill bacteria

Sep. 10, 2021—Vanderbilt researchers have identified a new antibacterial mechanism that could inspire novel strategies for combating staph and other extracellular bacterial pathogens.

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WIN for blocking cancer growth

Jan. 21, 2021—William Tansey and colleagues identified proteins that interact with the cancer drug target WDR5 and are important for cancer cell growth.

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One-two punch for cancer

Mar. 5, 2020—A drug combination effectively killed aggressive blood cancers in cell and animal models; now it’s being tested in patients.

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Grant bolsters research on myelodysplastic syndromes

Aug. 1, 2019—Michael Savona, MD, has received a competitive grant to develop therapies for patients with myelodysplastic syndromes.

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Cell death pathway implicated in bone marrow failure

Jan. 31, 2019—Vanderbilt investigators have linked a specific form of programmed cell death to myelodysplastic syndrome, a type of bone marrow failure.

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The yin and yang of COX-2

Oct. 2, 2015—New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs.

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