Florent Elefteriou Archives

Neurofibromin fine-tunes bone growth

May. 6, 2015—The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.

Inner ear keeps bones strong

Jan. 14, 2015—Alterations of the vestibular system - the part of our inner ear that controls balance - may contribute to bone loss related to both aging and space travel.

Bone healing therapy for NF1 fractures

Sep. 11, 2014—A combination treatment delivered to the site of fractures may improve bone healing in patients with the genetic disease neurofibromatosis type-1.

Novel treatment strengthens bones in genetic disease

Aug. 7, 2014—An enzyme therapy may prevent skeletal abnormalities associated with the genetic disorder neurofibromatosis type-1, Vanderbilt investigators have discovered.

Neurotransmitter’s role in bone balance

Nov. 7, 2013—Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling.

Factor’s role in long bone development

Jul. 31, 2013—Insight into how the protein neurofibromin participates in the signaling pathway that produces the body’s long bones has implications for fracture healing in some patients.

Studies outline new model for staph bone infections

Jun. 20, 2013—Osteomyelitis, a debilitating bone infection most frequently caused by Staphylococcus aureus (“staph”) bacteria, is particularly challenging to treat.

Inner ear’s role in bone remodeling

May. 15, 2013—The inner ear system that senses gravity and movement plays a role in bone remodeling – a finding that has clinical implications for space travel and for patients with inner ear disorders.

‘Longevity’ gene has role in bone loss

Dec. 6, 2012—A gene associated with long life participates in the normal regulation of bone remodeling and may have a role in bone loss associated with aging.