gastric cancer Archives
New marker for metaplasia
Oct. 14, 2021—A protein that transports water, called aquaporin 5, is expressed by cells undergoing changes that may increase risk for gastric cancer development, Vanderbilt researchers discovered.
Study finds genetic factor undermines H. pylori treatment
Aug. 4, 2021—Helicobacter pylori, a stomach-dwelling bacterium, is a strong risk factor for gastric cancer, peptic ulcers and other debilitating gastrointestinal disorders. Yet efforts to eradicate it using a combination of antibiotics and proton pump inhibitors (PPIs), which suppress gastric acid production, often fail.
Study gauges specific site stomach cancer risks among ethnic groups
Aug. 6, 2020—Non-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic white Americans. A new study breaks down this risk according to specific ethnicities and locations within the stomach.
Stomach bug hit-and-run
Jul. 23, 2020—The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate.
Researcher works on protocols to implement screening for gastric cancer
Apr. 2, 2020—A Vanderbilt gastroenterologist is helping lead an effort to establish screening guidelines for gastric cancer in the United States, where the number of people at risk for the cancer is increasing as the nation’s population becomes more diverse.
Powering H. pylori pathogenesis
Feb. 6, 2020—Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer.
VUMC study sheds light on gastric cancer development
Jan. 16, 2020—VUMC researchers have created the world’s first laboratory model of precancerous changes in the lining of the stomach, a scientific tour de force that is helping to unlock the mysteries of gastric cancer development.
A step toward gastric cancer
Oct. 3, 2019—New research findings provide insight into the detrimental events that develop in response to H. pylori infection.
Receptor’s role in stopping H. pylori
Apr. 25, 2019—The immune receptor NOD1 may be a prime target for preventing or treating H. pylori infections — the most significant risk factor for stomach cancer, Vanderbilt researchers have discovered.
Cancer prevention drug also disables H. pylori bacterium
Mar. 28, 2019—A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.
Early drivers of gastric cancer
Aug. 8, 2017—Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers.
New target for chronic infection
Feb. 2, 2017—An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered.
