gastric cancer Archives
Powering H. pylori pathogenesis
Feb. 6, 2020—Timothy Cover and colleagues report new insights into the sources of energy used by a bacterial “machine” linked to the pathogenesis of stomach cancer.
VUMC study sheds light on gastric cancer development
Jan. 16, 2020—VUMC researchers have created the world’s first laboratory model of precancerous changes in the lining of the stomach, a scientific tour de force that is helping to unlock the mysteries of gastric cancer development.
A step toward gastric cancer
Oct. 3, 2019—New research findings provide insight into the detrimental events that develop in response to H. pylori infection.
Receptor’s role in stopping H. pylori
Apr. 25, 2019—The immune receptor NOD1 may be a prime target for preventing or treating H. pylori infections — the most significant risk factor for stomach cancer, Vanderbilt researchers have discovered.
Cancer prevention drug also disables H. pylori bacterium
Mar. 28, 2019—A medicine currently being tested as a chemoprevention agent for multiple types of cancer has more than one trick in its bag when it comes to preventing stomach cancer, Vanderbilt researchers have discovered.
Early drivers of gastric cancer
Aug. 8, 2017—Using bioinformatics approaches, Vanderbilt investigators have identified gene expression networks that are deregulated in mouse and human stomach cancers.
New target for chronic infection
Feb. 2, 2017—An enzyme in macrophage immune cells may be a good target for treating chronic infections, Vanderbilt researchers have discovered.
A DARPP role in gastric cancer
Nov. 3, 2016—Vanderbilt researchers have discovered a link between Helicobacter pylori infection, inflammation and gastric cancer that could suggest new anti-cancer therapies.
Study suggests cancer’s ‘clock’ can be rewound
Mar. 17, 2016—Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented.
Stomach cancer cues
Aug. 6, 2015—Vanderbilt scientists have discovered a new molecular mechanism that promotes stomach cancer development, findings that could provide new opportunities for treatment.
Host sequesters zinc to control stomach bug
Nov. 21, 2014—Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk.
Human and Helicobacter co-evolution
Jan. 23, 2014—by Denise Anthony A Vanderbilt University-led research team has solved a long-standing riddle: Why do people of mostly Amerindian ancestry in the Andes have a gastric cancer rate that is 25 times higher than that of fellow Colombians of mostly African descent only 124 miles away on the coast? The answer is disruption of co-evolution...
