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Gastroenterology Hepatology and Nutrition Archives

A ‘supermere’ method for biomarker discovery

Apr. 6, 2023—Vanderbilt researchers have developed a method for isolating extracellular vesicles and nanoparticles — a complex transport system involved in health and disease — which will improve biomarker discovery and the identification of therapeutic targets.

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Horst takes on new roles in advancing digital health

Oct. 13, 2022—Sara Horst, MD, MPH, has been named associate vice chair for Digital Health Operations for Vanderbilt's Department of Medicine and assistant chief for Clinical Informatics for the Division of Gastroenterology, Hepatology and Nutrition.

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Study finds that reducing intake of simple sugars improves GERD

Oct. 6, 2022—A Vanderbilt study found that reducing dietary carbohydrates improved both symptoms and objective measurements of gastroesophageal reflux disease (GERD) in a randomized controlled trial.

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Video vital for telehealth visits

Jul. 28, 2022—Vanderbilt study of 18,130 telehealth visits at the beginning of the COVID-19 pandemic defines risk factors associated with telehealth access and suggests how health systems can improve access.

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New prognosis predictor and target for gastric cancer

Apr. 7, 2022—The protein CGA — a subunit of glycoprotein hormones — is a biomarker that predicts chemoresistance in gastric cancer and could be targeted along with EGFR to restore chemosensitivity.

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The role of polarity in early cancer

Sep. 21, 2021—Mutations in the protein epiregulin, an EGF receptor ligand, affect larger epithelial cell reorganization and may contribute to early cancer development, Vanderbilt researchers discovered.

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Probiotic protection

Mar. 4, 2021—A probiotic factor given early in life to mice prevented intestinal inflammation in adulthood, providing a rationale for probiotic intervention in individuals at high risk of developing inflammatory bowel disease.

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The role of diet in esophageal cancer

May. 4, 2020—New findings suggest that dietary calcium and magnesium affect the risk of esophageal cancer; if confirmed in interventional studies, they could inform dietary modifications to reduce the burden of this cancer.

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Potential new heartburn drug studied at VUMC

Feb. 26, 2020—An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.

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Initiative seeks to address malnutrition among adult patients

Feb. 22, 2018—It is estimated that nearly one out of five pediatric patients and one of three adult patients age 60 and older are malnourished and will experience a decline in their nutritional status during their hospital stay.

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Digestive Disease Research Center lands major grant

Jan. 19, 2017—The Vanderbilt Digestive Disease Research Center (VDDRC) celebrates its 15th anniversary this year with a third consecutive five-year renewal of its federal research grant.

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Patient’s liver transplant opens door to new life

Dec. 8, 2016—Erin Morris, 29, has much to be thankful for this holiday season, and at the top of her list is Roman Perri, M.D., assistant professor, Division of Gastroenterology, Hepatology, and Nutrition at Vanderbilt University Medical Center.

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