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Gastroenterology Hepatology and Nutrition Archives

New prognosis predictor and target for gastric cancer

Apr. 7, 2022—The protein CGA — a subunit of glycoprotein hormones — is a biomarker that predicts chemoresistance in gastric cancer and could be targeted along with EGFR to restore chemosensitivity.

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The role of polarity in early cancer

Sep. 21, 2021—Mutations in the protein epiregulin, an EGF receptor ligand, affect larger epithelial cell reorganization and may contribute to early cancer development, Vanderbilt researchers discovered.

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Probiotic protection

Mar. 4, 2021—A probiotic factor given early in life to mice prevented intestinal inflammation in adulthood, providing a rationale for probiotic intervention in individuals at high risk of developing inflammatory bowel disease.

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The role of diet in esophageal cancer

May. 4, 2020—New findings suggest that dietary calcium and magnesium affect the risk of esophageal cancer; if confirmed in interventional studies, they could inform dietary modifications to reduce the burden of this cancer.

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Potential new heartburn drug studied at VUMC

Feb. 26, 2020—An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests.

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Initiative seeks to address malnutrition among adult patients

Feb. 22, 2018—It is estimated that nearly one out of five pediatric patients and one of three adult patients age 60 and older are malnourished and will experience a decline in their nutritional status during their hospital stay.

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Digestive Disease Research Center lands major grant

Jan. 19, 2017—The Vanderbilt Digestive Disease Research Center (VDDRC) celebrates its 15th anniversary this year with a third consecutive five-year renewal of its federal research grant.

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Patient’s liver transplant opens door to new life

Dec. 8, 2016—Erin Morris, 29, has much to be thankful for this holiday season, and at the top of her list is Roman Perri, M.D., assistant professor, Division of Gastroenterology, Hepatology, and Nutrition at Vanderbilt University Medical Center.

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New treatment for Crohn’s disease

Mar. 22, 2016—A new biological therapy, ustekinumab, improves markers of disease activity in patients with severe Crohn’s disease.

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Clinicians, researchers team to treat boy’s rare disorder

Mar. 3, 2016—Test after test failed to reveal why Denny Majano wasn’t gaining weight or why he suffered from severe, chronic diarrhea. At 5 weeks old, instead of gaining weight as newborns should, Denny had lost a pound since birth.

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Protein interaction protects against neurodegeneration

Sep. 2, 2014—Two proteins interact to maintain selenium levels in the brain, and protect neurons from degeneration.

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Kudos: Read about faculty, staff and student honors, awards and achievements

Aug. 1, 2014—Read about faculty, staff and student honors, awards and achievements.

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