Gastroenterology Archives
New markers of colorectal cancer risk
Oct. 29, 2020—Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo.
Possible COVID-19 “decoy”
Oct. 15, 2020—It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection.
Factor involved in stomach injury response identified
Oct. 15, 2020—Researchers at Vanderbilt University Medical Center have identified a key factor that coordinates the body’s repair response to severe injury in the stomach caused, most commonly, by infection by the bacterium Helicobacter pylori.
Researchers create molecular ‘atlas’ of GI tract neurons
Oct. 8, 2020—Researchers at Vanderbilt University Medical Center have generated the first comprehensive molecular “atlas” of genes expressed by the neuronal cells within the intestine that coordinate the functions of the gastrointestinal (GI) tract.
Appendix cancer survival in young patients varies by race: study
Aug. 6, 2020—The first study of appendiceal cancer patterns and survival by race/ethnicity among patients younger than 50 in the U.S. showed survival disparities.
Study gauges specific site stomach cancer risks among ethnic groups
Aug. 6, 2020—Non-white Americans, especially Asian Americans, are at disproportionately higher risk for gastric cancer compared to non-Hispanic white Americans. A new study breaks down this risk according to specific ethnicities and locations within the stomach.
Study identifies novel genetic factors for colorectal cancer risk
Jan. 10, 2019—A large-scale study conducted among East Asians and led by Vanderbilt researchers has identified multiple, previously unknown genetic risk factors for colorectal cancer.
Bile acids mediate metabolic benefits of weight-loss surgery
Jan. 10, 2019—A team of Vanderbilt investigators has pinpointed the role of bile acids and a specific signaling pathway in the positive metabolic effects of weight-loss surgery.
Team isolates antibodies that neutralize GI bug norovirus
Aug. 30, 2018—Researchers at Vanderbilt University Medical Center have isolated the first human monoclonal antibodies that can neutralize norovirus, the leading cause of acute gastrointestinal illness in the world.
Study suggests cancer’s ‘clock’ can be rewound
Mar. 17, 2016—Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented.
Study sheds light on human gut’s ‘pacemaker’ cells
Jul. 30, 2015—The gut has its own built-in pacemakers, populations of specialized cells that control smooth muscle contraction in the stomach, small intestine and colon.
Improving patients’ quality of life drives Lind’s clinical care
Jul. 9, 2015—As a gastroenterologist, Christopher Lind, M.D., says he is often the “butt” of jokes, but few people truly appreciate the role the gut plays in their happiness.
