Researchers find potential new target against colorectal cancer
Jul. 21, 2022—by Bill Snyder Researchers at Vanderbilt University Medical Center have discovered a potential new target in the fight against colorectal cancer, the nation’s third most common malignancy and, next to lung cancer, the second leading cancer killer. This month in the journal Gastroenterology, R. Daniel Beauchamp, MD, Anna Means, PhD, and colleagues report that a...
Difficulty swallowing linked to chronic opioid use: study
Jul. 21, 2022—Vanderbilt researchers found that chronic use of opioid painkillers like hydrocodone and oxycodone significantly increases the risk of dysphagia, or difficulty swallowing.
Study reveals how gastric cancer forms, suggests preventive treatment
Jun. 23, 2022—Eunyoung Choi, PhD, assistant professor of Surgery, and colleagues identified for the first time that Trop2+/CD133+/CD166+ dysplastic stem cells are a key source of clonal evolution of dysplasia to multiple types of gastric cancer.
Study finds genetic factor undermines H. pylori treatment
Aug. 4, 2021—Helicobacter pylori, a stomach-dwelling bacterium, is a strong risk factor for gastric cancer, peptic ulcers and other debilitating gastrointestinal disorders. Yet efforts to eradicate it using a combination of antibiotics and proton pump inhibitors (PPIs), which suppress gastric acid production, often fail.
New Vanderbilt Health Hendersonville expands services in Sumner County
Mar. 30, 2021—Vanderbilt University Medical Center has opened Vanderbilt Health Hendersonville, a new 31,000-square-foot facility that offers adult outpatient specialty care, along with pediatric specialty care and imaging services to the citizens of Sumner and surrounding counties.
Gastroenterologist Merchant set for Discovery Lecture
Feb. 11, 2021—Juanita Merchant, MD, PhD, a nationally known gastroenterologist at the University of Arizona College of Medicine in Tucson, will discuss cellular changes that occur prior to gastric cancer during the next web-based Discovery Lecture.
Potential biomarker for IBD severity, cancer risk identified
Feb. 4, 2021—A selenium transport protein produced in the colon may be a novel biomarker for assessing disease severity and cancer risk in patients with inflammatory bowel disease.
New markers of colorectal cancer risk
Oct. 29, 2020—Vanderbilt epidemiologists identified new markers for colorectal cancer risk and characterized a previously unidentified tumor suppressor that regulates overall tumor volume in vivo.
Possible COVID-19 “decoy”
Oct. 15, 2020—It might be possible to use vesicles carrying the receptor for SARS-CoV-2, the virus that causes COVID-19, to bind the virus and prevent infection.
Factor involved in stomach injury response identified
Oct. 15, 2020—Researchers at Vanderbilt University Medical Center have identified a key factor that coordinates the body’s repair response to severe injury in the stomach caused, most commonly, by infection by the bacterium Helicobacter pylori.
Researchers create molecular ‘atlas’ of GI tract neurons
Oct. 8, 2020—Researchers at Vanderbilt University Medical Center have generated the first comprehensive molecular “atlas” of genes expressed by the neuronal cells within the intestine that coordinate the functions of the gastrointestinal (GI) tract.
Appendix cancer survival in young patients varies by race: study
Aug. 6, 2020—The first study of appendiceal cancer patterns and survival by race/ethnicity among patients younger than 50 in the U.S. showed survival disparities.