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Genetic Medicine Archives

Researchers develop framework for multiancestry genomic studies

Dec. 8, 2022—Vanderbilt researchers have developed a framework for the analysis of multiancestry, large-scale genomic studies across multiple biobanks.

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Surgery for hereditary breast cancer

Nov. 17, 2022—Similar rates of bilateral mastectomy in women with inherited mutations in high- and moderate-penetrance genes raises concerns about possible overtreatment of some patients, Vanderbilt researchers report.

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Embryo screening for mental illness questioned

Aug. 3, 2022—Report finds polygenic embryo screening (PES) does not provide an accurate measure of the risk of developing psychiatric disorders later in life.

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Longtime division leader earns degree, accolades

Jul. 21, 2022—Vanderbilt's Amy Shelton, MS, has been awarded a Master of Science Degree in Research Administration with Honors from the Johns Hopkins University Krieger School of Arts and Sciences.

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Three Vanderbilt biomedical researchers named 2022 Pew Scholars

Jun. 15, 2022—Mariana Byndloss, DVM, PhD, and William Wan, PhD, have been named 2022 Pew Scholars in the Biomedical Sciences and Alexander Bick, MD, PhD, was selected to join the 2022 class of Pew-Stewart Scholars for Cancer Research. 

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Genetics and blood pressure

May. 19, 2022—Including polygenic risk scores for blood pressure may improve predictive models to identify people at risk for treatment-resistant hypertension.

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Gene network linked to Type 2 diabetes

May. 5, 2022—Vanderbilt researchers used a novel analytical approach to identify a network of genes associated with Type 2 diabetes, including 31 genes that had not previously been associated with the disease.

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Study examines genetic risk for suicide attempt

Nov. 30, 2021—New research from Vanderbilt identifies the first replicated genomic region contributing to risk of suicide attempt and confirms that genetic risk for the trait is not driven solely by risk for psychiatric disorders.

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Study links genetic variants, protein expression and human diseases

Oct. 21, 2021—An international research team has developed a new resource that connects genetic variants and protein expression, which is expected to speed the identification of genes that cause disease — and point to novel treatment strategies.

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Study finds genetic risk factors for severe COVID-19 illness

Jul. 8, 2021—A massive worldwide collaboration including researchers from Vanderbilt University Medical Center (VUMC) has identified several genetic factors associated with SARS-CoV-2 infection and severe COVID-19 illness.

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Genetics of hydrocephalus

Jul. 8, 2021—Fluid build-up in the brain — hydrocephalus — increases pressure and risk for brain damage; Vanderbilt researchers have now identified genes and signaling pathways associated with the condition.

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VUMC joins national effort to improve disease prediction in diverse populations

Jun. 16, 2021—Vanderbilt University Medical Center will participate in a new federal initiative aimed at improving the use of polygenic risk scores (PRS) to predict complex diseases in diverse populations.

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