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genetic variant Archives

New breast cancer targets

May. 4, 2018—A special genetic analysis has revealed candidate genes associated with increased risk of breast cancer.

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Calcium intake and colorectal cancer

Oct. 18, 2017—Calcium intake appears to protect against colorectal cancer in individuals with certain gene variants, Vanderbilt researchers have discovered.

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NSAIDs, genetics and miscarriage

Sep. 20, 2017—A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.

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Culprits in genetic epilepsies

Oct. 11, 2016—Genetic variation in GABA-A receptors confers risk for inherited forms of epilepsy.

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New technique helps spot atrial fibrillation genetic variations

May. 8, 2014—A technique called whole-exome sequencing (WES) has been used for the first time at Vanderbilt University to identify new genetic variations associated with a common disease — a heart rhythm abnormality called atrial fibrillation (AF).

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Potential mechanism for myeloma drug’s variable toxicity

Apr. 30, 2014—A genetic variant is associated with toxicity of the chemotherapy drug melphalan, and could guide individualized dosing for the medication.

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A pain in the … genes

Jan. 10, 2014—Vanderbilt researchers have discovered that variation in the gene encoding the potassium channel GIRK1 plays a role in modulating human pain perception.

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Gene database to aid disease research

Jun. 19, 2012—A new catalog of human genetic data may help researchers uncover the genetic roots of disease and enable the ultimate realization of personalized medicine.

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New clue to ADHD

May. 15, 2012—A rare genetic change adds support to the idea that altered dopamine signaling is a key risk factor for ADHD.

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