Study revises understanding of cancer metabolism
Apr. 7, 2021—Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.
Gene variant and glucose metabolism
Feb. 18, 2021—Genetic variation that impacts glucose- and insulin-related signaling affects responses to type 2 diabetes treatments and warrants further study.
VUMC team’s discovery could lead to new diabetes treatment
Jun. 15, 2017—High circulating glucose, the hallmark of diabetes, is linked to the disease’s most serious complications including heart disease, kidney failure, blindness and amputation. Diabetes is the sixth leading cause of death and costs the nation an estimated $322 billion a year. Restoring the action of insulin has been the traditional treatment route. Insulin, a hormone...
Fat hormone’s role in zebrafish
Mar. 8, 2016—The hormone leptin regulates glucose balance, but not fat stores, in zebrafish.
Tiny model of diabetes
Feb. 20, 2015—Vanderbilt University researchers have created a zebrafish model of skeletal muscle insulin resistance that could help improve diabetes treatment.
Beta cell link to fasting glucose
Jan. 22, 2015—New findings explain why variation in a particular gene is the most important determinant of fasting blood glucose levels in humans.
Channel drug restores glucose balance
Apr. 16, 2014—A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis.
Better blood pressure-reducing drugs?
Apr. 30, 2012—A newer version of an old class of blood pressure lowering drugs may offer advantages for obese patients with metabolic syndrome.
Obesity turns “good” cholesterol bad
Mar. 21, 2012—Studies offer new insights into how obesity impairs the function of HDL, the “good” cholesterol.