The arrestin-GPCR connection
Apr. 11, 2019—Understanding details of how arrestins deactivate signaling by G-protein coupled receptors is key to the design of new therapeutics aimed at these cellular "inboxes" that are targeted by up to half of all pharmaceuticals.
Nobel laureate Kobilka set to deliver Flexner Discovery Lecture on April 5
Mar. 29, 2018—Brian Kobilka, MD, who shared the 2012 Nobel Prize in Chemistry for his studies of G protein-coupled receptors (GPCRs), will deliver the next Flexner Discovery Lecture on April 5.
New view of dopamine heteromers
Jan. 23, 2015—Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.
Shining a light on night blindness
Oct. 24, 2013—Vanderbilt researchers are studying how mutations in the receptor for light, rhodopsin, cause light blindness.
Seeing light receptor’s interactions
Jan. 18, 2013—Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.
Nobel in Chemistry reveals VU ties that bind
Oct. 18, 2012—Several Vanderbilt researchers have collaborated with this year's Nobel Chemistry winners.