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GPCR Archives

The arrestin-GPCR connection

Apr. 11, 2019—Understanding details of how arrestins deactivate signaling by G-protein coupled receptors is key to the design of new therapeutics aimed at these cellular "inboxes" that are targeted by up to half of all pharmaceuticals.

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Nobel laureate Kobilka set to deliver Flexner Discovery Lecture on April 5

Mar. 29, 2018—Brian Kobilka, MD, who shared the 2012 Nobel Prize in Chemistry for his studies of G protein-coupled receptors (GPCRs), will deliver the next Flexner Discovery Lecture on April 5.

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New view of dopamine heteromers

Jan. 23, 2015—Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.

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Shining a light on night blindness

Oct. 24, 2013—Vanderbilt researchers are studying how mutations in the receptor for light, rhodopsin, cause light blindness.

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Seeing light receptor’s interactions

Jan. 18, 2013—Understanding how the main receptor for light interacts with other signaling molecules may inform new pharmaceutical development.

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Nobel in Chemistry reveals VU ties that bind

Oct. 18, 2012—Several Vanderbilt researchers have collaborated with this year's Nobel Chemistry winners.

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