Guoqiang Gu Archives
Keeping beta cells “fit”
Jul. 9, 2020—Vanderbilt cell biologists are defining the factors that help beta cells in the pancreas stay healthy, secrete insulin and prevent diabetes initiation and progression.
New role for microtubules in diabetes
Jul. 29, 2019—Microtubules — part of the cell's cytoskeleton — regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes.
Microtubules act as cellular ‘rheostat’ to control insulin secretion
Dec. 3, 2015—Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell.
