heart disease Archives

Diabetes drugs associated with fewer adverse cardiac events in older veterans: study

May. 8, 2023—Vanderbilt research finds that GLP1 receptor agonists — a class of diabetes medications — are associated with fewer major adverse cardiovascular events than another type of diabetes drug (DPP4 inhibitors) in older veterans with no prior heart disease.

The study found that chronically disrupted sleep and highly variable sleep durations night after night may increase the risk for atherosclerosis.

Study finds chronically disrupted sleep may increase risk for heart disease

Feb. 15, 2023—Vanderbilt research found that sleep irregularity — chronically disrupted sleep and highly variable sleep durations night after night — may increase the risk for atherosclerosis.

Study may lead to new diabetes, heart disease treatments

Jan. 12, 2023—Vanderbilt research found that deletion of an autophagy-participating factor named PIK3C3 from the fat cells of mice led to compromised body temperature control, abnormal blood lipid levels, fatty liver and diabetes.

Reduced kidney function may cause cardiovascular disease: study

Dec. 15, 2022—An international team of investigators has found that mild to moderate reduction in kidney function may cause cardiovascular disease, even in people without symptoms of heart disease or diabetes.

VUMC leads effort to map heart disease-causing genetic variations

Sep. 13, 2022—Researchers from Vanderbilt University Medical Center, Stanford Medicine, the University of Toronto and Brigham and Women’s Hospital in Boston have joined forces to “map” the specific variations in more than 25 key cardiac disease genes that negatively affect heart function.

Heart patient Gabe Ezell, 11, recently visited Children’s Hospital’s new Fontan Clinic to check on his overall health in addition to his congenital heart condition. In the photo above, Gabe visits with Fontan team members Anita Pai, MD, left, and Angela Weingarten, MD.

Clinic offers ongoing care for pediatric heart patients

Jul. 13, 2022—Vanderbilt recently launched a new multidisciplinary Fontan Clinic, which will provide an ongoing, coordinated care plan for children and teens, ages 10-19, who have had the Fontan procedure for single ventricle heart disease.

BMI genetics influence heart function

Jun. 16, 2022—Vanderbilt researchers have discovered that a genetic predisposition to elevated body mass index increases the risk of diastolic dysfunction — a cardiac condition that can lead to heart failure.

Diabetes, cardiovascular drug targets

May. 24, 2022—Targeting receptors of the inflammatory lipid signaling molecule PGE2 may offer a new way to tackle both Type 2 diabetes and cardiovascular disease, Vanderbilt researchers have discovered.

Chest Pain Center receives reaccreditation from ACC

Mar. 3, 2022—Vanderbilt University Medical Center has been reaccredited as a Chest Pain Center with Primary Percutaneous Coronary Intervention (PCI) and Resuscitation.

Mariana Byndloss, DVM, PhD, Woongjae Yoo, PhD, and colleagues are studying how a high-fat diet may contribute to heart disease. (Photo taken prior to revised masking guidelines.)

Study reveals missing link between high-fat diet, microbiota and heart disease

Aug. 12, 2021—A high-fat diet disrupts the biology of the gut’s inner lining and its microbial communities — and promotes the production of a metabolite that may contribute to heart disease, according to a study published Aug. 13 in the journal Science.

From left, MacRae Linton, MD, Huan Tao, MD, PhD, Jonathan Brown, MD, and colleagues have discovered a potential new target for preventing atherosclerosis.

Nature’s “recycler” could reduce heart disease risk: study

Jul. 8, 2021—Researchers at Vanderbilt University Medical Center have identified potential new targets for the prevention of atherosclerosis through the enhancement of autophagy, a natural process for recycling damaged cellular material.

VUMC is pacesetter for national aspirin study

May. 20, 2021—According to an innovative large-scale clinical trial reported last week in the New England Journal of Medicine, a single daily baby aspirin (81 mg) or a single daily adult aspirin (325 mg) are equally safe and effective for prevention of adverse cardiovascular events for patients with established atherosclerotic cardiovascular disease.