heart rhythm Archives
A clue to an adverse drug event in children
May. 19, 2022—Considering metabolic (CYP2D6) enzyme activity score and patient age may aid in determining an individual’s risk for an adverse event with administration of the anti-arrhythmic drug propafenone.
Arrhythmia culprit: supertrafficking ion channel
Apr. 15, 2021—Charles Sanders, PhD, and colleagues show how a “supertrafficking” mutant potassium channel contributes to heart rhythm abnormalities.
Robotic technology speeds arrhythmia gene classification
Jun. 12, 2020—Vanderbilt University Medical Center investigators have used high-throughput robotic technology to rapidly study and classify variations in a gene linked to heart rhythm disorders and cardiac conditions.
New view of the heartbeat
Apr. 6, 2018—Structural views of the proteins that regulate the heartbeat may help improve existing treatments for cardiac arrhythmias.
Long QT syndrome – revealed
Mar. 12, 2018—Vanderbilt investigators have used sophisticated cell biological and structural techniques to “classify” mutations in potassium channels, studies that could lead to personalized treatment of heart rhythm disorders.
Mutation raises heart block risk
Mar. 3, 2017—A newly identified genetic risk factor for heart block after surgery may help guide the course of postoperative care.
Normalizing calcium flux to treat atrial fibrillation
May. 12, 2014—A particular anti-arrhythmia drug provides a targeted treatment for certain forms of atrial fibrillation.
Keeping the beat after heart surgery
Feb. 10, 2014—Variation in the gene for the beta-1 adrenergic receptor increases the risk that a patient will have an abnormal heart rhythm after cardiac surgery.
Rhythm response tied to gene variant
Jun. 21, 2013—A genetic variant that increases risk for atrial fibrillation also impacts the response to a common therapy for the heart rhythm disorder.
Study tracks genes involved in heart rhythm disorders
Feb. 7, 2013—A team led by Vanderbilt University investigators has discovered two new genes — both coding for the signaling protein calmodulin — associated with severe early-onset disorders of heart rhythm.
