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imaging mass spectrometry Archives

Bacterial battle in 3D

Jun. 2, 2022—Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing.

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H. pylori, lipid loss and stomach cancer

Jan. 17, 2022—H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered.

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Molecular imaging of C. diff infection

Sep. 30, 2021—C. difficile — the leading cause of hospital-associated intestinal infections — induces a rapid influx of bile acids into the gut, which could provide a novel target for blocking infection.

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Imaging host-pathogen battle for metal

Oct. 31, 2019—An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies.

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New look at atherosclerosis

Jul. 11, 2019—A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques.

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What protein is that?

Mar. 28, 2018—An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research.

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Mapping brain membrane proteins

Sep. 16, 2013—New mass spectrometry imaging methods will enable studies of the distribution and identification of membrane proteins directly within tissues.

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Team creates new view of body’s infection response

Aug. 9, 2012—A new 3-D view of the body’s response to infection — and the ability to identify proteins involved in the response — could point to novel biomarkers and therapeutic agents for infectious diseases.

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