immune response Archives
Rare disorder sheds light on dysbindin function
Jun. 27, 2023—A case study of a rare disorder uncovers roles for the protein dysbindin in the adaptive immune response and suggests that mutations may underlie some cases of very early onset inflammatory bowel disease.
Tracking lung macrophages
May. 4, 2023—A new technique will allow researchers to track subsets of immune cells that patrol and defend the lungs, to better understand the roles of these cells during lung inflammation, infection and injury.
Probing hellbender health
Feb. 20, 2023—Understanding how hellbenders — large, fully aquatic salamanders — fight fungal pathogens and disease is important for protecting these unique stream predators; Vanderbilt researchers add new insights.
A new view of a cholesterol carrier
Feb. 7, 2023—Vanderbilt researchers developed a novel method to measure small RNAs carried by HDL and demonstrated that these molecules circulate in greater concentrations than previously believed and are likely to contribute to communication between immune cells.
Study identifies key player in T cell “education”
Sep. 1, 2022—New Vanderbilt research could inform therapeutic strategies for enhancing thymic function when desired — such as during aging, recovery from radiation therapy or chemotherapy, or other conditions that reduce T cell output.
Bacterial battle in 3D
Jun. 2, 2022—Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing.
Youthful healing for burn wounds
Apr. 21, 2022—Topical treatment of burns with an immunosuppressive drug counteracted the negative effects of aging on wound healing, Vanderbilt researchers have discovered.
Study finds 10-second videos predict blood cancer relapse
Mar. 28, 2022—Vanderbilt research shows that 10-second videos of white blood cell motion in the skin’s microvasculature greatly improved the prediction of which stem cell and bone marrow transplant patients would have a relapse of their blood cancer.
Blood test figures in cancer risk for people with HIV
Mar. 17, 2022—A Vanderbilt study found that, among adult patients with HIV, those who have lower counts of certain types of blood cells have a markedly higher risk of developing cancer.
Who’s who in the respiratory landscape
Nov. 15, 2021—A metatranscriptomics method developed by Vanderbilt researchers simultaneously characterizes viruses, microbiome and host response in nasal swabs, opening opportunities to explore molecular interactions directly in clinical samples.
‘Pre-conditioning’ restores immune tolerance
Sep. 16, 2021—A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune disease and transplant rejection, Vanderbilt researchers discovered.
Autoimmunity advance
Aug. 24, 2021—Vanderbilt researchers have developed a high-throughput screening method to identify and characterize antigen-specific B cells — potential biomarkers for autoimmune disease and targets for new treatments.
