immune response Archives
Immune defenses in asthma
Apr. 5, 2016—Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease.
Melanoma response to immune therapy
Mar. 3, 2016—Melanoma-specific expression of a certain protein identifies tumors that are more responsive to an immune therapy.
Immune tolerance in endothelial cells
Jan. 7, 2016—Inducing “tolerance” to bacterial toxins in the endothelial cells that line blood vessels may offer a new approach for preventing the negative consequences of sepsis.
Tolerating a transplant
Oct. 1, 2015—A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease.
How to trick a wily virus
Jul. 24, 2015—Vanderbilt investigators have discovered how human antibodies induced during testing of an experimental “bird flu” vaccine kill the virus.
Immune response depends on force
Jan. 26, 2015—New studies explain how T-cell receptors use force to recognize and protect us against pathogens.
Host sequesters zinc to control stomach bug
Nov. 21, 2014—Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk.
Immune cell activity and melanoma
Nov. 6, 2014—The activity of a certain factor in immune cells is essential for an anti-tumor response, emphasizing the need to consider the effects of anti-cancer therapies on immune cells.
Peptide quells “genomic storm”
Oct. 28, 2014—A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.
Immune cells’ role in hypertension
Oct. 24, 2014—Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.
Aspirin and allergies
Oct. 10, 2014—Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies.
Natural killer cells don’t clear HMPV
Jul. 23, 2014—Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments.
