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immune response Archives

Immune cell activity and melanoma

Nov. 6, 2014—The activity of a certain factor in immune cells is essential for an anti-tumor response, emphasizing the need to consider the effects of anti-cancer therapies on immune cells.

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Peptide quells “genomic storm”

Oct. 28, 2014—A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.

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Immune cells’ role in hypertension

Oct. 24, 2014—Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.

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Aspirin and allergies

Oct. 10, 2014—Drugs such as aspirin and indomethacin may increase sensitivity to airborne allergens by suppressing production of the signaling molecule PGI2, which in turn may offer a new treatment for allergies.

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Natural killer cells don’t clear HMPV

Jul. 23, 2014—Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments.

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Regulating immune regulators

Jul. 17, 2014—Understanding how to control the generation of regulatory T cells could have important implications for treating autoimmunity and cancer.

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Study finds ‘hot’ frogs fight off fungal pathogen

Jul. 9, 2014—Simple heat treatments may give the frog immune system a boost and help it fight off a deadly fungal pathogen, according to a new study published July 10 in the journal Nature.

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HIV’s impact on B cells

Jan. 15, 2014—Understanding how HIV infection affects immune system B cells may guide strategies for vaccine development.

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Frog-killing fungus paralyzes amphibian immune response

Oct. 17, 2013—A fungus that is killing frogs and other amphibians around the world releases a toxic factor that disables the amphibian immune response, Vanderbilt University investigators report Oct. 18 in the journal Science.

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Probing intestinal immune cell roles

Aug. 28, 2013—A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.

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Nuclear shield against cell death

Aug. 8, 2013—The protein SARM appears to protect cells from inflammation-driven death by stabilizing the nuclear laminin scaffold.

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Target for inflammatory bowel disease

Mar. 1, 2013—The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.

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