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immune system Archives

Immune cells’ role in hypertension

Oct. 24, 2014—Vanderbilt researchers have discovered that certain immune cells contribute to the development of hypertension, suggesting novel targets for treating the disease.

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Immune cells that guard against ingested pathogens discovered

Oct. 9, 2014—Vanderbilt investigators have discovered a new type of immune cell residing in the intestinal epithelium that may function as a first line of defense against ingested pathogens.

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A path to sarcoidosis treatment

Sep. 25, 2014—Vanderbilt investigators identify a new therapeutic target for the inflammatory lung disease sarcoidosis.

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Natural killer cells don’t clear HMPV

Jul. 23, 2014—Understanding how the immune system responds to the respiratory virus HMPV is crucial for developing vaccines and anti-viral treatments.

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Regulating immune regulators

Jul. 17, 2014—Understanding how to control the generation of regulatory T cells could have important implications for treating autoimmunity and cancer.

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Obesity sends immune cells to the brain

Feb. 12, 2014—Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity.

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Probing intestinal immune cell roles

Aug. 28, 2013—A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.

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Study tracks skin salt’s role in blood pressure control

Jun. 6, 2013—Clinical pharmacologist Jens Titze, M.D., and his colleagues have identified a new cast of cells and molecules that function in the skin to control sodium balance and blood pressure.

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Study lays groundwork for rational T cell vaccine design

May. 30, 2013—Vanderbilt University investigators have developed a new strategy for identifying the “bits” of a pathogen that spark a protective immune response.

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“Silent” B cells trigger autoimmunity

Apr. 3, 2013—Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

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Do-it-yourself repair in the kidney

Jan. 31, 2013—The kidney can mediate its own repair through proliferation of resident immune system cells.

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New therapeutic target for cold, flu viruses identified

Aug. 9, 2012—Viruses that cause acute respiratory infections — such as human metapneumovirus (HMPV) and flu — impair a set of immune system cells that should clear the virus from the lungs. Now, Vanderbilt University investigators have discovered the signaling pathway that disables these immune cells.

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