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insulin Archives

Channel drug restores glucose balance

Apr. 16, 2014—A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis.

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Matrix remodeling and insulin resistance

Apr. 10, 2014—The extracellular matrix that surrounds cells plays a role in the development of insulin resistance.

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Is healthy obesity possible?

Jan. 29, 2014—It might be possible to generate a “metabolically healthy” state of obesity by targeting signaling pathways that improve insulin sensitivity.

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Searching for beta cell stimulators

Jan. 13, 2014—Vanderbilt researchers describe a new technique for identifying factors that stimulate the proliferation of pancreatic beta cells – factors that might offer therapeutic options for diabetes.

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Relaxin combats insulin resistance

Oct. 16, 2013—The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance.

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‘Yo-yo dieting’ inflames fat tissue

Aug. 9, 2013—Gaining and losing weight during “yo-yo dieting” may contribute to an exaggerated immune response in fat tissue that increases metabolic dysfunction more than steady weight gain alone.

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Matrix member key to insulin resistance

Jun. 6, 2013—A component of the extracellular matrix that surrounds cells plays a role in insulin resistance and may be a good therapeutic target.

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“Silent” B cells trigger autoimmunity

Apr. 3, 2013—Immune cells that recognize self antigens (e.g. insulin), but are functionally silent, can trigger autoimmune diseases such as diabetes.

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Discovery Lecture explores brain’s sensitivity to insulin

Feb. 28, 2013—Diabetes has a big impact on the brain.

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Pumping up the pancreas in pregnancy

Jan. 20, 2012—A strain of mutant mice provide a novel model for studying glucose intolerance and gestational diabetes during pregnancy and suggest that certain molecules may be useful for therapeutic applications.

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