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kidney failure Archives

VUMC scientists discover key step to kidney fibrosis

Nov. 21, 2023—Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury that can lead to kidney failure.

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ICU antibiotics may be safe for kidneys

Oct. 16, 2023—A Vanderbilt study found that two antibiotics thought to cause kidney failure in ICU patients with a severe bacterial infection, especially when combined with another antibiotic, may be safer for the kidneys than previously reported.

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Gene variants increase risk of kidney failure in veterans of African ancestry with COVID-19: study

Feb. 10, 2022—Gene variants increased the risk of acute kidney injury and death in veterans of African ancestry who were hospitalized with COVID-19, possibly explaining some health disparities associated with COVID-19.

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VUMC study raises hope for improving treatment of kidney disease

Feb. 2, 2022—Vanderbilt research has revealed an important mechanism in the kidney by which a cell surface receptor known as DDR1 fans the flames of inflammation and fibrosis that ultimately lead to kidney failure.

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VUMC, UCSF win KidneyX award for implantable home dialysis system

Jul. 22, 2020—A $500,000 KidneyX prize has been awarded to The Kidney Project — a collaboration between Vanderbilt University Medical Center and University of California, San Francisco (UCSF) — for the development of an implantable dialysis system that would enable patients to safely and effectively treat kidney failure at home.

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Implant one day may replace dialysis

May. 18, 2020—Vanderbilt researchers used pharmacological manipulations to increase salt and water transport by kidney cells grown in culture, a step necessary for realizing an implantable artificial kidney device.

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Vanderbilt investigators lead effort to create map of the human kidney

Oct. 31, 2019—Short of mandating universal diabetes treatment, regular exercise and low-calorie diets, little can be done to stem the rising tide of kidney failure — unless scientists can figure out why exactly the kidney’s filtration units, the glomeruli, stop working.

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Immune system a must for kidney repair

Nov. 12, 2015—A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells.

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Research effort seeks to improve home care for kidney failure patients

Jun. 27, 2013—Vanderbilt nephrologist, Thomas Golper, M.D., professor of Medicine in Nephrology and Hypertension, is leading an effort to form a research consortium with a goal of improving care for kidney failure patients who receive a form of home dialysis.

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‘Longevity’ gene aids kidney survival

Apr. 17, 2013—A gene associated with cell survival and longevity may protect the kidney from acute injury.

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Meds’ benefits differ in dialysis patients

Jan. 5, 2012—About half of kidney patients will die from heart disease within five years of starting dialysis, yet patients with kidney failure are rarely included in heart disease research. Jorge Gamboa, M.D., T. Alp Ikizler, M.D., and Nancy Brown, M.D., completed a small study that suggests a more personalized approach to selecting medication for heart disease...

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