Manuel Ascano Archives
Probing innate immunity
May. 19, 2020—Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.
New method captures early viral-host protein interactions
May. 7, 2020—Researchers have developed a method to identify the primary interactions between incoming viral RNA genomes and host proteins.
A switch for autoimmunity
Oct. 12, 2017—Vanderbilt investigators have discovered a class of compounds that inhibit a mediator of inflammation and autoimmune disorders, and that could pave the way for development of future therapies.
Ascano seeks to shed light on cellular stress response
Aug. 28, 2014—Ebola. Chikungunya. Influenza. What’s to be done about these headline-grabbing, debilitating, often lethal viruses?