Mass Spectrometry Research Center Archives
Bacterial battle in 3D
Jun. 2, 2022—Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing.
Imaging host-pathogen battle for metal
Oct. 31, 2019—An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies.
What protein is that?
Mar. 28, 2018—An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research.
New imaging approach offers unprecedented views of staph infection
Mar. 15, 2018—A new integrated imaging approach makes it possible to probe the molecules involved in invasive infections and can be broadly applied to any health or disease state.
VUMC investigators find pathogens work together to infect host
Nov. 3, 2016—Pseudomonas aeruginosa and Staphylococcus aureus — two pathogens that frequently co-infect the lungs of patients with cystic fibrosis — appear to cooperate with each other, Vanderbilt investigators have discovered. When pseudomonas is starved for metal by the host, it shuts down the production of factors that would normally kill staph, promoting a co-infection.
NIH grant bolsters mass spectrometry research initiatives
Aug. 11, 2016—The National Institutes of Health (NIH) has awarded a major renewal grant to continue the National Research Resource for Imaging Mass Spectrometry at Vanderbilt University School of Medicine.
Vanderbilt team first to blend high-end imaging techniques
Mar. 5, 2015—Vanderbilt University researchers have achieved the first “image fusion” of mass spectrometry and microscopy — a technical tour de force that could, among other things, dramatically improve the diagnosis and treatment of cancer.
Core facilities key driver of VUMC research gains
Jan. 29, 2015—During the past five years, Vanderbilt University Medical Center has become a leader in “personalized medicine,” the use of genomic information to individualize patient care.
VUMC research cores speed pace of discovery
Jan. 22, 2015—Progress against America’s most intractable health challenges, among them heart disease, cancer and diabetes, requires the best minds, the latest tools and the easy collaboration demanded by 21st century science.
Study tracks new way to fight HIV infection in women
Sep. 11, 2014—Vanderbilt University’s Richard Caprioli, Ph.D., is participating in a national, federally funded collaboration to develop an intravaginal ring capable of delivering antiretroviral drugs to women at risk for HIV infection.
Caprioli honored for mass spectrometry contributions
Jun. 19, 2014—Vanderbilt University’s Richard Caprioli, Ph.D., has received the 2014 Award for a Distinguished Contribution to Mass Spectrometry from the American Society for Mass Spectrometry (ASMS). Caprioli, the Stanford Moore Professor of Biochemistry and director of the Mass Spectrometry Research Center at Vanderbilt, was honored for development of Imaging Mass Spectrometry (IMS) using matrix-assisted laser desorption/ionization...
Mapping brain membrane proteins
Sep. 16, 2013—New mass spectrometry imaging methods will enable studies of the distribution and identification of membrane proteins directly within tissues.
