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metastasis Archives

Growth factor blockade targets breast tumors

Aug. 14, 2014—Inhibition of BMP growth factor signaling reduces breast tumor burden and metastasis.

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Protein’s role in spread of colon cancer studied

Apr. 3, 2014—One of the most formidable weapons in a cancer’s arsenal is the ability to spread to other organs.

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Cancer cells combine tools to increase invasiveness

Dec. 19, 2013—Two features of invasive cancer cells — invadopodia and exosomes — are linked together, Vanderbilt University investigators have discovered.

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Polarity protein suppresses tumor growth, invasion

Nov. 29, 2012—The machinery that builds the characteristic shape of epithelial cells suppresses breast cancer formation and metastasis in a mouse model.

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Proteins help flip tumor’s invasive switch

Oct. 4, 2012—Vanderbilt investigators have identified how two key components of cancer's invasive "switch" — the series of signaling events that turn on a tumor cell’s invasive behavior — work together.

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On the hunt for bladder cancer factors

Jul. 26, 2012—A protein linked to aggressive bladder cancers could point to new strategies for treatment or prevention.

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Proteins guard against cancer spread

Jul. 24, 2012—Targeting immune system proteins may keep prostate cancer from spreading to bone.

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VU study finds stress fuels breast cancer metastasis to bone

Jul. 18, 2012—Stress can promote breast cancer cell colonization of bone, Vanderbilt Center for Bone Biology investigators have discovered.

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Integrin curbs cancer’s spread

Feb. 16, 2011—Cell surface molecules called integrins have been found to play an important role when cancer metastasizes.

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