The plus and minus of microtubules
Sep. 5, 2019—Understanding the dynamic regulation of cytoskeletal microtubules may suggest new ways to treat disorders ranging from Alzheimer's disease to cancer.
New role for microtubules in diabetes
Jul. 29, 2019—Microtubules — part of the cell's cytoskeleton — regulate the secretion of insulin, suggesting that they may be a new target for treating diabetes.
How asters form
Aug. 2, 2018—New findings shed light on the formation of microtubule structures that support cellular processes ranging from cell division to intracellular transport.
Cell skeleton and the brush border
Jan. 31, 2018—Vanderbilt researchers have discovered a role for microtubules — part of the cellular “skeleton” — in organizing the unique sidedness of the epithelial cells that line organs like the intestines.
Research sheds light on how microtubules are assembled
Jan. 4, 2018—Microtubules are the “railroad tracks” essential for moving intracellular “freight” around in the cell. They’re also part of the spindle that pulls the two centrosomes apart during cell division.
Microtubules act as cellular ‘rheostat’ to control insulin secretion
Dec. 3, 2015—Microtubules — cellular “highways” that deliver cargo to the cell membrane for secretion — have a surprising role in pancreatic beta cells. Instead of facilitating glucose-stimulated insulin secretion, they limit it, a team of Vanderbilt investigators reported recently in Developmental Cell.
Zanic’s journey to the lab followed winding path
Mar. 5, 2015—It’s roughly 5,000 miles from Croatia to Tennessee as the crow flies.
VU study reveals factor’s new role in cell division, migration
Oct. 30, 2014—Vanderbilt University investigators have discovered a new molecular mechanism that regulates microtubule dynamics. The unexpected finding, reported in Developmental Cell, has implications for cancer drug discovery.